Spinal muscular atrophy (SMA) is a lower motor neuron disease with autosomal recessive
inheritance. The first cases of SMA were reported by Werdnig in 1891. Although the …

Spinal muscular atrophy is a monogenic, progressive motor neuron disorder caused by
deletion or mutation in the SMN1 gene. A broad range of phenotypic severity, from very …

Spinal muscular atrophy (SMA) is a congenital neuromuscular disorder characterized by
motor neuron loss, resulting in progressive weakness. SMA is notable in the health care …

Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by loss of
motor neurons in the anterior horn of the spinal cord and resultant weakness. The most …

Spinal muscular atrophy (SMA) is characterized by muscle weakness and atrophy resulting
from progressive degeneration and irreversible loss of the anterior horn cells in the spinal …

Spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by mutations in
SMN1 (encoding survival motor neuron protein (SMN)). Reduced expression of SMN leads …

Twenty-five years ago, the underlying genetic cause for one of the most common and
devastating inherited diseases in humans, spinal muscular atrophy (SMA), was identified …

Until the recent development of disease-modifying therapeutics, spinal muscular atrophy
(SMA) was considered a devastating neuromuscular disease with a poor prognosis for most …

Spinal muscular atrophy (SMA) is a potentially devastating and lethal neuromuscular
disease frequently manifesting in infancy and childhood. The discovery of the underlying …

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease caused
by deletions or mutations in the survival motor neuron (SMN1) gene. SMA is characterized …