Soluble receptors to vascular endothelial growth factor (VEGF) can inhibit its angiogenic
effect. Since angiogenesis is involved in wound repair, we hypothesized that adenovirus …

It has been previously shown that vascular endothelial growth factor (VEGF) plays a central
role in promoting angiogenesis during wound repair and that healing-impaired diabetic mice …

Vascular endothelial growth factor (VEGF) is a potent paracrine signal for initiating
angiogenesis. Although VEGF can bind to several cell surface receptors, VEGF receptor …

Diabetes impairs numerous aspects of tissue repair. Failure of wound angiogenesis is
known to delay diabetic wound healing, whereas the importance of lymphangiogenesis for …

Diminished production of vascular endothelial growth factor (VEGF) and decreased
angiogenesis are thought to contribute to impaired tissue repair in diabetic patients. We …

Objective—VEGF-ENZ7/PlGF molecules composed of Orf virus-derived VEGF-ENZ7 and
human PlGF1 were previously proven to be potent angiogenic factors stimulating …

VEGF and Angiopoietin (Ang) 1 are growth factors that independently improve wound
healing outcomes. Using a tet-repressible mouse model coupled with streptozotocin …

In this study, we hypothesize that local sustained release of vascular endothelial growth
factor (VEGF), using adenovirus vector (ADV)-mediated gene transfer, accelerates …

Chronic wounds represent a major therapeutic challenge. Lymphatic vessel function is
impaired in chronic ulcers but the role of lymphangiogenesis in wound healing has …

VEGF family members play important roles in angiogenesis and vascular permeability.
VEGF-A-transgenic mice showed an increased vascularization with edema due to hyper …