Pelvic inflammatory disease (PID) results from ascension of sexually transmitted pathogens
from the lower genital tract to the uterus and/or fallopian tubes in women, with potential …

The Gram-negative human pathogen N. gonorrhoeae (Ngo) quickly attaches to epithelial
cells, and large numbers of the bacteria remain on the cell surface for prolonged periods …

Infection with Neisseria gonorrhoeae (N. gonorrhoeae) can trigger an intense local
inflammatory response at the site of infection, yet there is little specific immune response or …

The endocervical epithelium is a major reservoir for Chlamydia trachomatis in women, and
genital infections are extended in their duration. Epithelial cells act as mucosal sentinels by …

Neisseria gonorrhoeae is a bacterial pathogen responsible for the sexually transmitted
infection gonorrhea. Emergence of antimicrobial resistance (AMR) of N. gonorrhoeae …

Chlamydia trachomatis causes a predominantly asymptomatic, but generally inflammatory,
genital infection that is associated with an increased risk for HIV acquisition. Endocervical …

The mechanism (s) by which Lactobacillus-dominated cervicovaginal microbiota provide a
barrier to Chlamydia trachomatis infection remain (s) unknown. Here we evaluate the impact …

Colonization of the endometrium by pathogenic bacteria ascending from the lower female
reproductive tract (FRT) is associated with many gynecologic and obstetric health …

Little is known about the pathogenesis of gonococcal infection within the lower female
genital tract. We recently described the distribution of complement receptor 3 (CR3) on …

Neisseria gonorrhoeae secrets a phospholipase D (NgPLD), which augments complement
receptor 3 (CR3)‐mediated invasion of cervical epithelial cells. To elucidate the signalling …