Publisher Summary Molecular characterization of a family of melatonin (N-acetyl-5-
methoxytryptamine) receptors has provided the foundation for new avenues of exploration …

Melatonin is a widely distributed hormone that regulates several major physiological
processes, including the circadian rhythm and seasonal adaptation. The two subtypes of …

A novel series of melatonin receptor ligands, characterized by a N-(substituted-anilinoethyl)
amido scaffold, along with preliminary structure–activity relationships (SARs), is presented …

The various physiological actions of the neurohormone melatonin are mediated mainly by
two G-protein-coupled MT1 and MT2 receptors. The melatoninergic drugs on the market …

Melatonin (5-methoxy-acetyl tryptamine) is a sleep-inducing hormone, and the pineal gland
produces it in response to the circadian clock of darkness. In the body, MT1 and MT2 …

Melatonin exerts many of its actions through the activation of two G protein-coupled
receptors (GPCRs), named MT1 and MT2. So far, a number of different MT1 and MT2 …

The search for melatonin receptor agonists formed the main part of melatonin medicinal
chemistry programs for the last three decades. In this short review, we summarize the two …

Melatonin (N-acetyl-5-methoxytryptamine) is synthesized and released by the pineal gland
following a circadian rhythm characterized by high levels during the night. It shows several …

Melatonin receptors MT1 and MT2 are G protein-coupled receptors that mediate the effects
of melatonin, a hormone involved in circadian rhythms and other physiological functions …

Melatonin receptors (MT1 and MT2 in humans) are family AG protein–coupled receptors that
respond to the neurohormone melatonin to regulate circadian rhythm and sleep. Numerous …