Melatonin, or 5-methoxy-N-acetyltryptamine, is synthesized and released by the pineal
gland and locally in the retina following a circadian rhythm, with low levels during the day …

Melatonin, N‐acetyl‐5‐methoxytryptamine, an evolutionally old molecule, is produced by the
pineal gland in vertebrates, and it binds with high affinity to melatonin receptors, which are …

A series of N-(2-phenylbenzofuran-3-yl) ethyl amide and N-(2-arylalkylbenzofuran-3-yl) ethyl
amide derivatives were synthesized and evaluated as melatonin receptor ligands. The …

A new family of melatonin receptor ligands, characterized by a tetrahydroquinoline (THQ)
scaffold carrying an amide chain in position 3, was devised as conformationally constrained …

Melatonin is a neurohormone released in a circadian manner with peak levels at night.
Melatonin mediates its effects mainly through G protein-coupled MT1 and MT2 receptors …

Integrated in silico chemical clustering and melatonin receptor molecular modeling
combined with in vitro 2-[125I]-iodomelatonin competition binding were used to identify …

Aim: Melatonin (MT) is a neurohormone produced and secreted primarily by the pineal
gland in a circadian manner, and mainly acts through 2 receptor subtypes: MT 1 and MT 2 in …

Melatonin is the principal hormone secreted by the pineal gland, produced in humans with a
circadian rhythm characterized by elevated blood levels during the night. It is involved in the …

Melatonin, the hormone of darkness, is secreted in minute amounts during the night and is
virtually undetectable during the day. Melatonin mainly acts on high-affinity G protein …

The labeled ligand commonly employed in competition binding studies for melatonin
receptor ligands, 2‐[125I] iodomelatonin, showed slow dissociation with different half‐lives …