Objectives Vasculopathy is an important hallmark of systemic chronic inflammatory
connective tissue diseases (CICTD) and is associated with increased cardiovascular risk …

Cardiovascular risk is increased in patients with autoimmune rheumatic diseases.
Endothelial, erythrocyte and platelet microvesicles (MVs) are elevated in patients with …

Systemic autoimmune diseases are a group of disorders featured by humoral and cell-
mediated immune responses against several self-molecules. Despite the fact that diagnostic …

Objective. To improve knowledge of vasculopathy in SSc through the assessment of serum
levels of circulating angiogenetic and endothelial dysfunction markers in patients at different …

Objective An association between systemic autoimmune diseases and atherosclerosis has
been described in many connective tissue diseases, and this association is known to lead to …

Vascular disease is a hallmark of systemic sclerosis (SSc). It is present in every patient,
being responsible both for the earliest clinical manifestations and the major life-threatening …

Objective. Limited cutaneous systemic sclerosis (lcSSc) is characterised by vasculopathy
contributing to vascular apoptosis, structural and functional changes. The aim of this study …

Objective. We evaluated potential circulating biomarkers of disease activity in giant cell
arteritis (GCA), Takayasu arteritis (TA), polyarteritis nodosa (PAN), and eosinophilic …

Background Systemic sclerosis (SSc) features autoimmunity, vasculopathy and tissue
fibrosis. The renin-angiotensin and endothelin systems have been implicated in …

AIM: Evidence is accumulating for endothelial cell dysfunction as one of the main factors
initiating vessel wall damage in SLE. Enhanced expression of endothelial adhesion …