[HTML][HTML] Biocompatible copolymer formulations to treat glioblastoma multiforme

LCS Erthal, OL Gobbo, E Ruiz-Hernandez - Acta biomaterialia, 2021 - Elsevier
The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years
while the prognosis for the patients is still poor and most of them survive less than 1 year …

[HTML][HTML] Biomaterials: Emerging systems for study and treatment of glioblastoma

JR Aguilera-Márquez, GT de Dios-Figueroa… - Neurology …, 2022 - Elsevier
Introduction Glioblastoma (GBM), the most frequent type of brain tumour in adults, is highly
aggressive and invasive. No curative treatment is currently available for GBM; patient …

Biodegradable polymer implants to treat brain tumors

H Brem, P Gabikian - Journal of controlled release, 2001 - Elsevier
We have developed a systematic approach for the discovery and evaluation of local
treatment strategies for brain tumors using polymers. We demonstrated the feasibility of …

Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma

C Bastiancich, P Danhier, V Préat, F Danhier - Journal of Controlled …, 2016 - Elsevier
Among central nervous system tumors, Glioblastoma (GBM) is the most common, aggressive
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …

Advanced biomaterials for human glioblastoma multiforme (GBM) drug delivery

Z Nozhat, S Heydarzadeh, M Shahriari-Khalaji… - Biomaterials …, 2023 - pubs.rsc.org
Glioblastoma multiforme (GBM) has several distinctive characteristics linked to a poor early-
stage prognosis. The crucial obstacle in the treatment of GBM is the inability of chemo drugs …

Injectable hydrogels for localized chemotherapy and radiotherapy in brain tumors

P de la Puente, N Fettig, MJ Luderer, A Jin… - Journal of …, 2018 - Elsevier
Overall survival of patients with newly diagnosed glioblastoma (GBM) remains dismal at 16
months with state-of-the-art treatment that includes surgical resection, radiation, and …

[HTML][HTML] Development of polymer-based nanoformulations for glioblastoma brain cancer therapy and diagnosis: An update

B Rabha, KK Bharadwaj, S Pati, BK Choudhury… - Polymers, 2021 - mdpi.com
Brain cancers, mainly high-grade gliomas/glioblastoma, are characterized by uncontrolled
proliferation and recurrence with an extremely poor prognosis. Despite various conventional …

[HTML][HTML] Design of biopolymer-based interstitial therapies for the treatment of glioblastoma

ES Pena, EG Graham-Gurysh, EM Bachelder… - International journal of …, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is the most common form of primary brain cancer and has
the highest morbidity rate and current treatments result in a bleak 5-year survival rate of …

[HTML][HTML] Local delivery to malignant brain tumors: Potential biomaterial-based therapeutic/adjuvant strategies

M Alghamdi, M Gumbleton, B Newland - Biomaterials Science, 2021 - pubs.rsc.org
Glioblastoma (GBM) is the most aggressive malignant brain tumor and is associated with a
very poor prognosis. The standard treatment for newly diagnosed patients involves total …

Polymeric drugs based on bioactive glycosides for the treatment of brain tumours

MLL Donaire, J Parra-Cáceres, B Vázquez-Lasa… - Biomaterials, 2009 - Elsevier
Polymeric drugs carrying glycolipids have been designed as target macromolecules for the
treatment of brain tumours. A methacrylate derivative of oleyl 2-acetamido-2-deoxy-α-d …