Altered glycosylation is a universal feature of cancer cells, and certain glycans are well-
known markers of tumor progression. This chapter discusses glycan biosynthetic pathways …

Altered glycosylation is a universal feature of cancer cells, and certain glycan structures are
well-known markers for tumor progression. This chapter discusses some glycan biosynthetic …

Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Glycosylation is catalyzed by various glycosyltransferase enzymes which are mostly located
in the Golgi apparatus in cells. These enzymes glycosylate various complex carbohydrates …

Neoplastic transformation results in a wide variety of cellular alterations that impact the
growth, survival, and general behavior of affected tissue. Although genetic alterations …

The change of cellular glycosylation is one of the key events in malignant transformation and
neoplastic progression, and tumor‐related glycosylation alterations are promising targets in …

Aberrant glycosylation occurs in essen-tially all types of experimental and human cancers,
as has been observed for over 35 years, and many glycosyl epitopes constitute tumor …

Many noninherited human diseases are caused or influenced by acquired changes in
glycan synthesis or recognition. This chapter lists a few examples, their proposed …

Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …