Before the advent of neuroprotective therapy with hypothermia, studies evaluating outcomes
of children born at term with birth depression or encephalopathy were generally cohort …

Background Therapeutic hypothermia reduces the risk of death, or moderate to severe
neurodevelopmental impairment (NDI) in term infants with hypoxic-ischemic …

Objective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal
mortality and neurodisability. We aimed to determine the incidence of HIE and management …

Aim To examine the relationship between electrographic seizures and long‐term outcome in
neonates with hypoxic–ischemic encephalopathy (HIE). Method Full‐term neonates with HIE …

Objectives: To define the 1‐year neurodevelopmental outcome for survivors of moderate
(Sarnat stage 2) neonatal hypoxic‐ischaemic encephalopathy (HIE) to facilitate appropriate …

Importance Hypoxic-ischemic encephalopathy (HIE) occurs in 1 to 8 per 1000 live births in
developed countries. Historically, the clinician has had little to offer neonates with HIE other …

Background Therapeutic hypothermia (TH) is regarded as the most efficacious therapy for
neonatal hypoxic encephalopathy. However, limitations in previous systematic reviews and …

Objectives To determine the long-term neurodevelopmental outcome for children after
hypoxic-ischemic encephalopathy (HIE) without major disability, and to examine neonatal …

Mohamed Tagin, MB, BCh1, Hesham Abdel-Hady, PhD2, Sajjad ur Rahman, MBBS, DCH,
MCPS, FCPS, FRCPCH3, 4, Denis V. Azzopardi, FRCPCH5, and Alistair J. Gunn, MBChB …

BACKGROUND/AIMS: Post-asphyxia neonatal encephalopathy (NE) is one of the main
causes of disabilities in term-born infants. This review attempted to investigate the …