Hypoxic-ischemic encephalopathy and therapeutic hypothermia: the hemodynamic perspective

RE Giesinger, LJ Bailey, P Deshpande… - The Journal of …, 2017 - jpeds.com
Hypoxic-ischemic encephalopathy (HIE) is a severe central nervous system injury in
neonates secondary to perinatal asphyxia. It may cause devastating lifelong neurocognitive …

Hypothermia for perinatal asphyxia: trial-based quality of life at 6–7 years

H Campbell, O Eddama, D Azzopardi… - Archives of disease in …, 2018 - adc.bmj.com
Objective To assess the impact of hypothermic neural rescue at birth on health-related
quality of life (HRQL) in middle childhood. Design Six-year to 7-year follow-up of surviving …

Neonatal hypoxic-ischemic encephalopathy diagnosis and treatment: a National Survey in China

Z Wang, P Zhang, W Zhou, S Xia, W Zhou, X Zhou… - BMC pediatrics, 2021 - Springer
Background Neonatal hypoxic-ischemic encephalopathy (HIE) affects as many as 100,000
infants each year in China. Therapeutic hypothermia reduces HIE related mortality and long …

Role of EEG background activity, seizure burden and MRI in predicting neurodevelopmental outcome in full-term infants with hypoxic-ischaemic encephalopathy in the …

LC Weeke, GB Boylan, RM Pressler, B Hallberg… - European Journal of …, 2016 - Elsevier
Objective To investigate the role of EEG background activity, electrographic seizure burden,
and MRI in predicting neurodevelopmental outcome in infants with hypoxic-ischaemic …

Does aetiology of neonatal encephalopathy and hypoxic–ischaemic encephalopathy influence the outcome of treatment?

S Mcintyre, N Badawi, E Blair… - … Medicine & Child …, 2015 - Wiley Online Library
Neonatal encephalopathy, a clinical syndrome affecting term‐born and late preterm
newborn infants, increases the risk of perinatal death and long‐term neurological morbidity …

LyTONEPAL: long term outcome of neonatal hypoxic encephalopathy in the era of neuroprotective treatment with hypothermia: a French population-based cohort

T Debillon, N Bednarek, A Ego… - BMC pediatrics, 2018 - Springer
Background Hypoxic-ischemic encephalopathy (HIE) is a rare neonatal condition affecting
about 1‰ births. Despite a significant improvement in the management of this condition in …

Therapeutic hypothermia initiated within 6 hours of birth is associated with reduced brain injury on MR biomarkers in mild hypoxic-ischaemic encephalopathy: a non …

P Montaldo, PJ Lally, V Oliveira, R Swamy… - Archives of Disease in …, 2019 - fn.bmj.com
Objective To examine the effect of therapeutic hypothermia on MR biomarkers and
neurodevelopmental outcomes in babies with mild hypoxic-ischaemic encephalopathy …

Electroencephalography and brain magnetic resonance imaging in asphyxia comparing cooled and non-cooled infants

ATT Leen, S Ouwehand, M Olsthoorn, P Govaert… - european journal of …, 2019 - Elsevier
Objective The aim was to establish any differences in the predictive value of EEG and MRI
for outcome in infants treated and not-treated with therapeutic hypothermia (HT) for perinatal …

A review of the conundrum of mild hypoxic-ischemic encephalopathy: Current challenges and moving forward

L Chalak, S Latremouille, I Mir, PJ Sánchez… - Early human …, 2018 - Elsevier
A review of the conundrum called mild hypoxic-ischemic encephalopathy (HIE) is provided.
During the past decades, the definition of HIE has evolved to accommodate the short …

Implementation of neonatal neurocritical care program improved short-term outcomes in neonates with moderate-to-severe hypoxic ischemic encephalopathy

S Roychoudhury, MJ Esser, J Buchhalter… - Pediatric Neurology, 2019 - Elsevier
Background Despite the introduction of therapeutic hypothermia, infants with moderate-to-
severe hypoxic-ischemic encephalopathy remain at risk of mortality and morbidity. A …