The identification of individual or clusters of predictive genetic alterations might help in
defining the outcome of cancer treatment, allowing for the stratification of patients into …

Genetic discoveries and treatment advances in neuroblastoma : Current Opinion in
Pediatrics Genetic discoveries and treatment advances in neuroblastoma : Current Opinion …

Currently, patients with neuroblastoma are classified into risk groups (eg, according to the
Children's Oncology Group risk-stratification) to guide physicians in the choice of the most …

Cancer is a complex disease driven by multiple genetic and epigenetic alterations.
Understanding the (epi-) genetic changes and consequent deregulation of regulatory …

Purpose The knowledge of the key genomic events that are causal to cancer development
and progression not only is invaluable for our understanding of cancer biology but also may …

Purpose: Neuroblastoma is an embryonal tumor with contrasting clinical courses. Despite
elaborate stratification strategies, precise clinical risk assessment still remains a challenge …

Neuroblastoma is one of the most common solid tumors in children. Its clinical behavior
ranges widely from spontaneous regression to life‐threatening aggressive growth. The …

BACKGROUND: Current risk stratification systems for neuroblastoma patients consider
clinical, histopathological, and genetic variables, and additional prognostic markers have …

Background More accurate prognostic assessment of patients with neuroblastoma is
required to better inform the choice of risk-related therapy. The aim of this study is to develop …

Microarray-based prediction of clinical endpoints may be performed using either a one-color
approach reflecting mRNA abundance in absolute intensity values or a two-color approach …