Background Recent studies suggest an association between the Interferon Inducible
Transmembrane 3 (IFITM3) rs12252 variant and the course of influenza infection. However …

Abstract Purpose of Review Interferon-induced transmembrane protein 3 (IFITM3) is a
cellular restriction factor that blocks fusion between virus and host membranes. Here, we …

Importance Severe coronavirus disease 2019 (COVID-19) can occur in younger,
predominantly male, patients without preexisting medical conditions. Some individuals may …

Abstract Interferon lambda 4 (IFNλ4) has shown antiviral activity against RNA viruses,
including some coronaviruses. Besides, genetic variants of IFNL4 can be predictive of the …

It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human lung …

Background. Interferon-induced transmembrane protein 3 (IFITM3) restricts endocytic fusion
of influenza virus. IFITM3 rs12252_C, a putative alternate splice site, has been associated …

Summary Interferon‐γ‐inducible protein 16 (IFI 16) plays a pivotal role in the death of
bystander CD 4+ T‐cells. Here, we demonstrate that SNP rs1417806 in IFI 16 is associated …

Background IFITM3 has been suggested to be associated with infection in some ethnic
groups. Diabetes and hypercholesterolemia are also important clinical conditions that can …

Cytokines, small proteins (5-20kDa) required in cell signaling and as immunomodulating
agents in human body. Now, these cell signals are known to mediate many inflammatory …

The 2009 H1N1 influenza pandemic, which involved a more pathogenic virus than seasonal
influenza viruses, rapidly spread around the world and caused many deaths in humans. The …