Tripeptide LSW, initially identified as a potent ACE inhibitory peptide from soybean protein,
was recently reported to exert a protective effect against angiotensin II-induced endothelial …

An emerging inference is that vascular cells transfer their biological cargo to recipient cells
by secretion of extracellular vesicles (EVs). This study explored the effects of EVs produced …

Phenotype switch of vascular smooth muscle cells (VSMCs) plays an important role in the
development of atherosclerosis (AS). Endothelial cells can regulate VSMC phenotypic …

Oxidized low-density lipoprotein (ox-LDL) stimulation impairs the oxidation-reduction
equilibrium in vascular endothelial cells (VECs) and contributes to atherosclerosis (AS). This …

The excessive accumulation of angiotensin II (Ang II) in the vascular microenvironment
promotes vascular dysfunction including vascular endothelial inflammation and remodeling …

Soybean is a rich source of high-quality proteins and an excellent food source of bioactive
peptides. A tripeptide, Leu–Ser–Trp (LSW), was previously identified from soybean as an …

Defects in the low-density lipoprotein receptor (LDLR) are associated with familial
hypercholesterolemia (FH), manifested by atherosclerosis and cardiovascular disease …

Circular RNAs (circRNAs) are a group of RNAs featured by a covalently closed continuous
loop structure. This study aimed to uncover the function and mechanism of circ‐ubiquitin …

Atherosclerosis is a chronic lipid-induced inflammation of the vessel wall. Oxidized low-
density lipoprotein was confirmed to drive the onset of atherogenesis. Zinc finger e-box …

Objective Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is the major
receptor for oxidized LDL in endothelial cells. LOX-1 is highly expressed in atherosclerotic …