Engineering drug delivery systems (DDS) aim to release bioactive cargo to a specific site
within the human body safely and efficiently. Hydrogels have been used as delivery matrices …

Nanoparticles have offered a unique set of properties for drug delivery including high drug
loading capacity, combinatorial delivery, controlled and sustained drug release, prolonged …

In order to control their release, drugs are encapsulated into systems which are expected to
provide a certain site with a predetermined amount of drug over a well-defined period of …

Uncontrollable displacements that greatly affect the concentration of active agents at the
target tissues are among a major limitation of the use of microparticulate drug delivery …

Controlling the release of bioactive agents has important potential applications in tissue
engineering. While microspheres have been investigated to manipulate release rates, the …

Hydrogel-based depots typically tend to remain where injected and have excellent
biocompatibility but are relatively poor at controlling drug release. Nanoparticles (NPs) …

Hydrogels are water-soluble polymer networks that are similar to the extracellular matrix of
cells. Drug delivery systems based on hydrogels are of interest given their high …

In this contribution, a novel smart drug delivery system (DDS) consisting of hydroxyl-
functionalized glycerol poly (ε-caprolactone)(PGCL)-based microspheres and poly (N …

A variety of microparticles have been proposed for the sustained and localized delivery of
drugs with the objective of increasing therapeutic indexes by circumventing filtering organs …

Clinically available medications face several hurdles that limit their therapeutic activity,
including restricted access to the target tissues due to biological barriers, low bioavailability …