The causality between intestinal flora and allergic diseases: Insights from a bi-directional two-sample Mendelian randomization analysis

Q Jin, F Ren, D Dai, N Sun, Y Qian, P Song - Frontiers in immunology, 2023 - frontiersin.org
Background Growing evidence shows a significant association between intestinal flora and
allergic diseases, specifically atopic dermatitis (AD), allergic rhinitis (AR), and allergic …

Gut microbiota and atopic dermatitis: a two-sample Mendelian randomization study

Y Xue, L Zhang, Y Chen, H Wang, J Xie - Frontiers in Medicine, 2023 - frontiersin.org
Background Accumulating evidence suggests that alterations in gut microbiota composition
and diversity are associated with Atopic dermatitis (AD). But until now, the causal …

Assessing causal relationships between gut microbiota and asthma: evidence from two sample Mendelian randomization analysis

R Li, Q Guo, J Zhao, W Kang, R Lu, Z Long… - Frontiers in …, 2023 - frontiersin.org
Background Accumulating evidence has suggested that gut microbiota dysbiosis is
commonly observed in asthmatics. However, it remains unclear whether dysbiosis is a …

Association of atopic dermatitis with autoimmune diseases: A bidirectional and multivariable two-sample mendelian randomization study

W Zhou, J Cai, Z Li, Y Lin - Frontiers in Immunology, 2023 - frontiersin.org
Background Observational studies have suggested the association between atopic
dermatitis (AD) and the risks of autoimmune diseases. It is still unclear, however, whether or …

Mendelian randomization analysis reveals a complex genetic interplay among atopic dermatitis, asthma, and gastroesophageal reflux disease

K Ahn, RB Penn, S Rattan, RA Panettieri Jr… - American journal of …, 2023 - atsjournals.org
Rationale: Gastroesophageal reflux disease (GERD) is commonly associated with atopic
disorders, but cause–effect relationships remain unclear. Objectives: We applied Mendelian …

Clarifying the effect of gut microbiota on allergic conjunctivitis risk is instrumental for predictive, preventive, and personalized medicine: a Mendelian randomization …

K Liu, Y Cai, K Song, R Yuan, J Zou - EPMA Journal, 2023 - Springer
Background Allergic conjunctivitis is an ocular immune disease which affects the
conjunctiva, eyelids, and cornea. Growing evidence implicates the gut microbiota in …

The association between intestinal bacteria and allergic diseases—cause or consequence?

P Han, JQ Gu, LS Li, XY Wang, HT Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
The incidence of allergic disorders has been increasing over the past few decades,
especially in industrialized countries. Allergies can affect people of any age. The …

Two-sample Mendelian randomization analysis investigates causal associations between gut microbial genera and inflammatory bowel disease, and specificity …

B Liu, D Ye, H Yang, J Song, X Sun, Y Mao… - Frontiers in …, 2022 - frontiersin.org
Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD).
Ulcerative colitis (UC) and Crohn's disease (CD), two subtypes of IBD, are characterized by …

Assessment of causal direction between gut microbiota and inflammatory bowel disease: a Mendelian randomization analysis

ZJ Zhang, HL Qu, N Zhao, J Wang, XY Wang… - Frontiers in …, 2021 - frontiersin.org
Background Recent studies have shown that the gut microbiota is closely related to the
pathogenesis of Inflammatory Bowel Disease (IBD), but the causal nature is largely …

Gut microbiota and allergic diseases in children

S Akagawa, K Kaneko - Allergology International, 2022 - jstage.jst.go.jp
abstract The gut microbiota resides in the human gastrointestinal tract, where it plays an
important role in maintaining host health. The human gut microbiota is established by the …