[HTML][HTML] Evaluation of the early-phase [18F] AV45 PET as an optimal surrogate of [18F] FDG PET in ageing and Alzheimer's clinical syndrome

M Vanhoutte, B Landeau, S Sherif, V de la Sayette… - NeuroImage: Clinical, 2021 - Elsevier
Abstract Dual-phase [18 F] AV45 positron emission tomography (PET) is highly promising in
the assessment of neurodegenerative diseases, allowing to obtain information on both …

[18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer's disease

A Li, R Zhao, M Zhang, P Sun, Y Cai, L Zhu… - European Journal of …, 2024 - Springer
Abstract Purpose [18F]-D3FSP is a new β-amyloid (Aβ) PET imaging tracer designed to
decrease nonspecific signals in the brain by reducing the formation of the N-demethylated …

18F-APN-1607 Tau Positron Emission Tomography Imaging for Evaluating Disease Progression in Alzheimer's Disease

X Xu, W Ruan, F Liu, Y Gai, Q Liu, Y Su… - Frontiers in Aging …, 2022 - frontiersin.org
Purpose 18F-APN-1607 is a novel tau positron emission tomography (PET) tracer
characterized with high binding affinity for 3− and 4-repeat tau deposits. The aim was to …

Accuracy of tau positron emission tomography as a prognostic marker in preclinical and prodromal Alzheimer disease: a head-to-head comparison against amyloid …

R Ossenkoppele, R Smith, N Mattsson-Carlgren… - JAMA …, 2021 - jamanetwork.com
Importance Tau positron emission tomography (PET) tracers have proven useful for the
differential diagnosis of dementia, but their utility for predicting cognitive change is unclear …

Early [18F]florbetaben and [11C]PiB PET images are a surrogate biomarker of neuronal injury in Alzheimer's disease

S Tiepolt, S Hesse, M Patt, J Luthardt… - European journal of …, 2016 - Springer
Purpose [18 F] FDG is a commonly used neuronal injury biomarker for early and differential
diagnosis of dementia. Typically, the blood supply to the brain is closely coupled to glucose …

Correlation between brain 18F-AV45 and 18F-FDG PET distribution characteristics and cognitive function in patients with mild and moderate Alzheimer's disease

J Jing, F Zhang, L Zhao, J Xie, J Chen… - Journal of …, 2021 - content.iospress.com
Background: Florbetapir (AV45) and fluorodeoxyglucose (FDG) PET imaging are valuable
techniques to detect the amyloid-β (Aβ) load and brain glucose metabolism in patients with …

18F–FDG PET diagnostic and prognostic patterns do not overlap in Alzheimer's disease (AD) patients at the mild cognitive impairment (MCI) stage

S Morbelli, M Bauckneht, D Arnaldi, A Picco… - European journal of …, 2017 - Springer
Purpose We aimed to identify the cortical regions where hypometabolism can predict the
speed of conversion to dementia in mild cognitive impairment due to Alzheimer's disease …

Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer's disease

A Drzezga, D Altomare, C Festari, J Arbizu… - European journal of …, 2018 - Springer
Purpose To assess the clinical utility of 18F-Fluorodeoxyglucose positron emission
tomography (FDG-PET) for detection of early signs of neurodegeneration in conditions of …

Tau positron emission tomographic imaging in aging and early A lzheimer disease

KA Johnson, A Schultz, RA Betensky… - Annals of …, 2016 - Wiley Online Library
Objective Detection of focal brain tau deposition during life could greatly facilitate accurate
diagnosis of Alzheimer disease (AD), staging and monitoring of disease progression, and …

Dual time-point [18F] florbetaben PET delivers dual biomarker information in mild cognitive impairment and Alzheimer's disease

L Florek, S Tiepolt, ML Schroeter… - Journal of …, 2018 - content.iospress.com
Background: Current research diagnostic criteria for Alzheimer's disease (AD) and mild
cognitive impairment (MCI) due to AD include biomarkers to supplement clinical testing …