Regenerative medicine (RM) is an interdisciplinary field that aims to repair, replace or
regenerate damaged or missing tissue or organs to function as close as possible to its …

Extracellular vesicles (EVs), which are the main paracrine components of stem cells, mimic
the regenerative capacity of these cells. Stem cell-derived EVs (SC-EVs) have been used for …

One of the most promising approaches to stimulate regeneration and angiogenesis in
traumatic or ischemic tissue damage is stem cell therapy. Embryonic and fetal stem cells …

The intense research focus on stem and progenitor cells could be attributed to their
differentiation potential to generate new cells to replace diseased or lost cells in many highly …

Cell transplantation therapy has certain limitations including immune rejection and limited
cell viability, which seriously hinder the transformation of stem cell-based tissue …

Stem cells act in a paracrine manner through the secretion of biologically active cargo that
acts on cells locally and systemically. These active molecules include not only soluble …

Stem cells, with their therapeutic potential in tissue repair and regeneration, have been
widely used in translational medicine. Recent evidence suggests that the beneficial effects …

Stem cells are critical to maintaining steady-state organ homeostasis and regenerating
injured tissues. Recent intriguing reports implicate extracellular vesicles (EVs) as carriers for …

The rapid progress in the field of stem cell research has laid strong foundations for their use
in regenerative medicine applications of injured or diseased tissues. Growing evidences …

Sepsis remains a serious and life-threatening disease with high morbidity and mortality. Due
to the unique immunomodulatory, anti-inflammatory, anti-apoptotic, anti-microbial, anti …