[PDF][PDF] Molecular evaluation of Tuberculosis agents on a H9c2 rat ventricular cardiomyoblast model.
C Februarie, M Blignaut, KI Tapfuma - 2023 - scholar.sun.ac.za
Tuberculosis (TB) remains a significant global health challenge, demanding ongoing
assessment of the efficacy and safety of its therapeutic agents. This study focused on …
assessment of the efficacy and safety of its therapeutic agents. This study focused on …
An in silico approach to identify potential inhibitors against multiple drug targets of Mycobacterium tuberculosis
S Kumar, P Sahu, L Jena - The International Journal of …, 2019 - journals.lww.com
Background: The increasing incidence of multidrug-resistant cases of tuberculosis (TB) and
difficulty in treating these cases requires an urgent need to find an effective anti-TB drug …
difficulty in treating these cases requires an urgent need to find an effective anti-TB drug …
Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics
E Elmorsy, SM Attalla, E Fikry, A Kocon… - Human & …, 2017 - journals.sagepub.com
Tuberculosis (TB) is an intractable chronic infection. Disease treatment with anti-TB drugs
remains challenging due to drug-induced hepatotoxicity. The toxicity of the anti-TB drugs …
remains challenging due to drug-induced hepatotoxicity. The toxicity of the anti-TB drugs …
Modeling Host-Pathogen Interaction to Elucidate the Metabolic Drug Response of Intracellular Mycobacterium tuberculosis
RA Rienksma, PJ Schaap… - Frontiers in cellular …, 2019 - frontiersin.org
Little is known about the metabolic state of Mycobacterium tuberculosis (Mtb) inside the
phagosome, a compartment inside phagocytes for killing pathogens and other foreign …
phagosome, a compartment inside phagocytes for killing pathogens and other foreign …
New Drugs and Novel Cellular Targets against Tuberculosis
Mycobacterium tuberculosis (Mtb) is the etiological agent of tuberculosis (TB), one of the
most life-threatening communicable diseases, which causes 10 million new cases each year …
most life-threatening communicable diseases, which causes 10 million new cases each year …
Evaluation of mitochondrial oxidative toxicity in mammalian cardiomyocytes by determining the highly reproducible and reliable increase in mitochondrial superoxides …
Mitochondria are important cytoplasmic elements present in eukaryotic cells, and are
involved in converting energy to ATP through oxidative phosphorylation. Mitochondria are …
involved in converting energy to ATP through oxidative phosphorylation. Mitochondria are …
Establishment of a platform for measuring mitochondrial oxygen consumption rate for cardiac mitochondrial toxicity
The heart has an abundance of mitochondria since cardiac muscles require copious
amounts of energy for providing continuous blood through the circulatory system, thereby …
amounts of energy for providing continuous blood through the circulatory system, thereby …
Molecular analysis of mitochondrial compromise in rodent cardiomyocytes exposed long term to nucleoside reverse transcriptase inhibitors (NRTIs)
Despite the highly effective impact of NRTI therapy in patients infected with the human
immunodeficiency virus type 1 (HIV-1), long-term treatment has revealed cardiotoxicity …
immunodeficiency virus type 1 (HIV-1), long-term treatment has revealed cardiotoxicity …
Challenges in drug discovery against tuberculosis
M Dwivedi, P Giri - Molecular Epidemiology Study of …, 2021 - books.google.com
Tuberculosis (TB) is one of the deadly diseases in the present era caused by Mycobacterium
tuberculosis. Principally, this bacterium attacks the lungs, however, MTB Has been observed …
tuberculosis. Principally, this bacterium attacks the lungs, however, MTB Has been observed …
[引用][C] P12-17 Changes in superoxides showed a reproducible and accurate screening method for mitochondrial toxicity in drug-treated mammalian cardiomyocytes
D Ahn, CW Kim, KC Choi - Toxicology Letters, 2022 - Elsevier