Stealthy microbes: How Neisseria gonorrhoeae hijacks bulwarked iron during infection
JL Stoudenmire, AN Greenawalt… - Frontiers in Cellular and …, 2022 - frontiersin.org
Transition metals are essential for metalloprotein function among all domains of life.
Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins …
Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins …
Metal piracy by Neisseria gonorrhoeae to overcome human nutritional immunity
The bacterium Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhea.
N. gonorrhoeae is an obligate human pathogen that colonizes mucosal surfaces of the …
N. gonorrhoeae is an obligate human pathogen that colonizes mucosal surfaces of the …
Transition metals at the host–pathogen interface: how Neisseria exploit human metalloproteins for acquiring iron and zinc
Transition metals are essential nutrients for all organisms and important players in the host–
microbe interaction. During bacterial infection, a tug-of-war between the host and microbe …
microbe interaction. During bacterial infection, a tug-of-war between the host and microbe …
Neisseria gonorrhoeae Modulates Iron-Limiting Innate Immune Defenses in Macrophages
Neisseria gonorrhoeae is a strict human pathogen that causes the sexually transmitted
infection termed gonorrhea. The gonococcus can survive extracellularly and intracellularly …
infection termed gonorrhea. The gonococcus can survive extracellularly and intracellularly …
Acclimation to Nutritional Immunity and Metal Intoxication Requires Zinc, Manganese, and Copper Homeostasis in the Pathogenic Neisseriae
AH Branch, JL Stoudenmire, KL Seib… - Frontiers in Cellular …, 2022 - frontiersin.org
Neisseria gonorrhoeae and Neisseria meningitidis are human-specific pathogens in the
Neisseriaceae family that can cause devastating diseases. Although both species inhabit …
Neisseriaceae family that can cause devastating diseases. Although both species inhabit …
Metal-limited growth of Neisseria gonorrhoeae for characterization of metal-responsive genes and metal acquisition from host ligands
S Maurakis, CN Cornelissen - JoVE (Journal of Visualized Experiments), 2020 - jove.com
Trace metals such as iron and zinc are vital nutrients known to play key roles in prokaryotic
processes including gene regulation, catalysis, and protein structure. Metal sequestration by …
processes including gene regulation, catalysis, and protein structure. Metal sequestration by …
Characterization of the effects of iron on Neisseria gonorrhoeae surface protein modulation and host cell interactions
A Oki - 2014 - scholarscompass.vcu.edu
Iron is an essential nutrient that is sequestered by iron-binding proteins in the human host
resulting in a hostile environment for microbes. Neisseria gonorrhoeae, however, can utilize …
resulting in a hostile environment for microbes. Neisseria gonorrhoeae, however, can utilize …
Mechanisms of iron acquisition employed by Neisseria gonorrhoeae for survival within cervical epithelial cells
TA Hagen - 2006 - scholarscompass.vcu.edu
Neisseria gonowhoeae has evolved a repertoire of high-affinity iron acquisition systems to
facilitate essential iron uptake in the human host. Acquisition of iron requires both the energy …
facilitate essential iron uptake in the human host. Acquisition of iron requires both the energy …
Neisseria gonorrhoeae requires expression of TonB and the putative transporter TdfF to replicate within cervical epithelial cells
TA Hagen, CN Cornelissen - Molecular microbiology, 2006 - Wiley Online Library
Neisseria gonorrhoeae has evolved a repertoire of iron acquisition systems that facilitate
essential iron uptake in the human host. Acquisition of iron requires both the energy …
essential iron uptake in the human host. Acquisition of iron requires both the energy …
Mutagenesis of the Loop 3 α-Helix of Neisseria gonorrhoeae TdfJ Inhibits S100A7 Binding and Utilization
SA Maurakis, JL Stoudenmire, JK Rymer, WJ Chazin… - Mbio, 2022 - Am Soc Microbiol
Neisseria gonorrhoeae causes the sexually transmitted infection (STI) gonorrhea, which
afflicts over 80 million people each year. No vaccine is available to prevent gonorrhea. The …
afflicts over 80 million people each year. No vaccine is available to prevent gonorrhea. The …