Modular gene analysis reveals distinct molecular signatures for subsets of patients with cutaneous lupus erythematosus
JL Zhu, LT Tran, M Smith, F Zheng, L Cai… - British Journal of …, 2021 - academic.oup.com
Background Cutaneous lupus erythematosus (CLE) is a heterogeneous autoimmune
disease with clinical sequelae such as itching, dyspigmentation and scarring. Objectives We …
disease with clinical sequelae such as itching, dyspigmentation and scarring. Objectives We …
[HTML][HTML] Genome-wide transcriptional profiling of chronic cutaneous lupus erythematosus (CCLE) peripheral blood identifies systemic alterations relevant to the skin …
R Dey-Rao, AA Sinha - Genomics, 2015 - Elsevier
Major gaps remain regarding pathogenetic mechanisms underlying clinical heterogeneity in
lupus erythematosus (LE). As systemic changes are likely to underlie skin specific …
lupus erythematosus (LE). As systemic changes are likely to underlie skin specific …
Genome-wide transcriptional profiling data from skin of chronic cutaneous lupus erythematosus (CCLE) patients
R Dey-Rao, AA Sinha - Data in Brief, 2015 - data-in-brief.com
Cutaneous features manifest as a wide range of clinically significant, and in many cases
disfiguring and debilitating components of lupus erythematosus (LE). While the definitive …
disfiguring and debilitating components of lupus erythematosus (LE). While the definitive …
[HTML][HTML] Differential gene expression analysis in CCLE lesions provides new insights regarding the genetics basis of skin vs. systemic disease
Lupus erythematosus is a heterogeneous autoimmune condition affecting multiple organs
including skin, which remains poorly understood. To investigate pathogenetic processes …
including skin, which remains poorly understood. To investigate pathogenetic processes …
[HTML][HTML] The genetic landscape of cutaneous lupus erythematosus
HW Chen, G Barber, BF Chong - Frontiers in Medicine, 2022 - frontiersin.org
Cutaneous lupus erythematosus (CLE) is an autoimmune, connective tissue disease that
can exist as its own disease entity or within the context of systemic lupus erythematosus …
can exist as its own disease entity or within the context of systemic lupus erythematosus …
Molecular profiling of cutaneous lupus lesions identifies subgroups distinct from clinical phenotypes
CC Berthier, LC Tsoi, TJ Reed, JN Stannard… - Journal of clinical …, 2019 - mdpi.com
Cutaneous lupus erythematosus (CLE) is a common manifestation of systemic lupus
erythematosus (SLE), and CLE can also develop without systemic involvement. CLE can be …
erythematosus (SLE), and CLE can also develop without systemic involvement. CLE can be …
Bioinformatics analyses of gene expression profile identify key genes and functional pathways involved in cutaneous lupus erythematosus
Z Gao, L Su, Q Wu, J Sheng, Y Wang, Y Dai… - Clinical …, 2022 - Springer
Background Lupus erythematosus is an autoimmune disease that causes damage to
multiple organs ranging from skin lesions to systemic manifestations. Cutaneous lupus …
multiple organs ranging from skin lesions to systemic manifestations. Cutaneous lupus …
Genome‐wide association study identifies new susceptibility loci for cutaneous lupus erythematosus
Cutaneous lupus erythematosus (CLE) is a chronic autoimmune disease of the skin with
typical clinical manifestations. Here, we genotyped 906 600 single nucleotide …
typical clinical manifestations. Here, we genotyped 906 600 single nucleotide …
Pathogenesis of cutaneous lupus
GA Hile, A Schuler, JM Kahlenberg - Dubois' Lupus Erythematosus and …, 2025 - Elsevier
Cutaneous lupus erythematosus (CLE) is a potentially disfiguring condition frequently
associated with systemic lupus erythematosus (SLE). CLE lesions are characteristically …
associated with systemic lupus erythematosus (SLE). CLE lesions are characteristically …
B cell signatures distinguish cutaneous lupus erythematosus subtypes and the presence of systemic disease activity
L Abernathy-Close, S Lazar, J Stannard… - Frontiers in …, 2021 - frontiersin.org
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory skin disease characterized
by a diverse cadre of clinical presentations. CLE commonly occurs in patients with systemic …
by a diverse cadre of clinical presentations. CLE commonly occurs in patients with systemic …