Modular gene analysis reveals distinct molecular signatures for subsets of patients with cutaneous lupus erythematosus

JL Zhu, LT Tran, M Smith, F Zheng, L Cai… - British Journal of …, 2021 - academic.oup.com
Background Cutaneous lupus erythematosus (CLE) is a heterogeneous autoimmune
disease with clinical sequelae such as itching, dyspigmentation and scarring. Objectives We …

[HTML][HTML] Genome-wide transcriptional profiling of chronic cutaneous lupus erythematosus (CCLE) peripheral blood identifies systemic alterations relevant to the skin …

R Dey-Rao, AA Sinha - Genomics, 2015 - Elsevier
Major gaps remain regarding pathogenetic mechanisms underlying clinical heterogeneity in
lupus erythematosus (LE). As systemic changes are likely to underlie skin specific …

Genome-wide transcriptional profiling data from skin of chronic cutaneous lupus erythematosus (CCLE) patients

R Dey-Rao, AA Sinha - Data in Brief, 2015 - data-in-brief.com
Cutaneous features manifest as a wide range of clinically significant, and in many cases
disfiguring and debilitating components of lupus erythematosus (LE). While the definitive …

[HTML][HTML] Differential gene expression analysis in CCLE lesions provides new insights regarding the genetics basis of skin vs. systemic disease

R Dey-Rao, JR Smith, S Chow, AA Sinha - Genomics, 2014 - Elsevier
Lupus erythematosus is a heterogeneous autoimmune condition affecting multiple organs
including skin, which remains poorly understood. To investigate pathogenetic processes …

[HTML][HTML] The genetic landscape of cutaneous lupus erythematosus

HW Chen, G Barber, BF Chong - Frontiers in Medicine, 2022 - frontiersin.org
Cutaneous lupus erythematosus (CLE) is an autoimmune, connective tissue disease that
can exist as its own disease entity or within the context of systemic lupus erythematosus …

Molecular profiling of cutaneous lupus lesions identifies subgroups distinct from clinical phenotypes

CC Berthier, LC Tsoi, TJ Reed, JN Stannard… - Journal of clinical …, 2019 - mdpi.com
Cutaneous lupus erythematosus (CLE) is a common manifestation of systemic lupus
erythematosus (SLE), and CLE can also develop without systemic involvement. CLE can be …

Bioinformatics analyses of gene expression profile identify key genes and functional pathways involved in cutaneous lupus erythematosus

Z Gao, L Su, Q Wu, J Sheng, Y Wang, Y Dai… - Clinical …, 2022 - Springer
Background Lupus erythematosus is an autoimmune disease that causes damage to
multiple organs ranging from skin lesions to systemic manifestations. Cutaneous lupus …

Genome‐wide association study identifies new susceptibility loci for cutaneous lupus erythematosus

M Kunz, IR König, A Schillert, J Kruppa… - Experimental …, 2015 - Wiley Online Library
Cutaneous lupus erythematosus (CLE) is a chronic autoimmune disease of the skin with
typical clinical manifestations. Here, we genotyped 906 600 single nucleotide …

Pathogenesis of cutaneous lupus

GA Hile, A Schuler, JM Kahlenberg - Dubois' Lupus Erythematosus and …, 2025 - Elsevier
Cutaneous lupus erythematosus (CLE) is a potentially disfiguring condition frequently
associated with systemic lupus erythematosus (SLE). CLE lesions are characteristically …

B cell signatures distinguish cutaneous lupus erythematosus subtypes and the presence of systemic disease activity

L Abernathy-Close, S Lazar, J Stannard… - Frontiers in …, 2021 - frontiersin.org
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory skin disease characterized
by a diverse cadre of clinical presentations. CLE commonly occurs in patients with systemic …