Tumor models have created new avenues for personalized medicine and drug
development. A new culture model derived from a three-dimensional system, the tumor …

The recent advances in in vitro 3D culture technologies, such as organoids, have opened
new avenues for the development of novel, more physiological human cancer models. Such …

Malignant tumors are one of the leading causes of death which impose an increasingly
heavy burden on all countries. Therefore, the establishment of research models that closely …

Organoids are established through in vitro 3D culture, and they can mimic the structure and
physiological functions of organs or tissues in vivo. Organoids have attracted much attention …

An accumulation of previous work has established organoids as good preclinical models of
human tumors, facilitating translation from basic research to clinical practice. They are …

Tumor organoids are 3D cultures of cancer cells that can be derived on an individual patient
basis with a high success rate. This creates opportunities to build large biobanks with …

Cancer harbors variable heterogeneity and plasticity. Thus far, our comprehension is greatly
based on cell lines, organoids, and patient-derived tumor xenografts (PDTXs). Organoids …

Recent advances in biofabrication technologies, such as cell culture systems, and
biomaterials have led to the development of three-dimensional (3D) cell culture platforms …

Organoid models allow for the study of key pathophysiological processes such as cancer
biology in vitro. They offer insights into all aspects covering tumor development, progression …

Simple Summary Despite significant strides in multimodal therapy, cancers still rank within
the first three causes of death especially in industrial nations. A lack of individualized …