Human concern about the status of genetic diversity in livestock breeds and their
conservation has increased, as intense selection and reduced population sizes in many …

Zygote-microinjection or in vitro electroporation of isolated zygotes are now widely used
methods to produce genome-edited mice. However, these technologies require laborious …

Recent advances in the CRISPR/Cas9 system have demonstrated it to be an efficient gene‐
editing technology for various organisms. Laboratory mice and rats are widely used as …

Cytosine base editors (CBEs) enable programmable C-to-T conversion without DNA double-
stranded breaks and homology-directed repair in a variety of organisms, which exhibit great …

Genome editing technology is a technique for targeted genetic modifications, enabling the
knockout and addition of specific DNA fragments. This technology has been widely used in …

Genetically modified swine hold great promise in the fields of agriculture and medicine.
Currently, these swine are being used to optimize production of quality meat, to improve our …

The CRISPR/Cas9 genome editing tool has the potential to improve the livestock breeding
industry by allowing for the introduction of desirable traits. Although an efficient and targeted …

Background Genome editing technologies provide new tools for genetic improvement and
have the potential to become the next game changer in animal and plant breeding. The aim …

© The American Society of Gene & Cell Therapy commentary remaining embryos are
destroyed. This practice is now performed routinely to avoid pregnancy with embryos …

Although the laboratory rabbit has long contributed to many paradigmatic studies in biology
and medicine, it is often considered to be a “classical animal model” because in the last 30 …