Novel insights into the complex architecture of osteoporosis molecular genetics
FA Saad - Annals of the New York Academy of Sciences, 2020 - Wiley Online Library
Osteoporosis is a prevalent osteodegenerative disease and silent killer linked to a decrease
in bone mass and decline of bone microarchitecture, due to impaired bone matrix …
in bone mass and decline of bone microarchitecture, due to impaired bone matrix …
Research progress of signaling pathways in osteoporosis
Y Zhang, Z Shen - Chinese Journal of Orthopaedics, 2017 - pesquisa.bvsalud.org
Osteoporosis is a systemic metabolic degenerative skeletal disease, characterized by
reduced bone mass and disrupted bone microarchitecture, leading to enhanced bone …
reduced bone mass and disrupted bone microarchitecture, leading to enhanced bone …
RETRACTED ARTICLE: Key genes associated with osteoporosis revealed by genome wide gene expression analysis
J Chen, L Wang, Y Shen, J Yu, T Ye, C Zhuang… - Molecular biology …, 2014 - Springer
Gene expression profiles of circulating monocytes were analyzed to identify key genes
associated with osteoporosis. Raw microarray data were downloaded from gene expression …
associated with osteoporosis. Raw microarray data were downloaded from gene expression …
[PDF][PDF] The genetics of osteoporosis
GR Clark, EL Duncan - Br Med Bull, 2015 - Citeseer
Introduction: Osteoporosis is the commonest metabolic bone disease worldwide. The clinical
hallmark of osteoporosis is low trauma fracture, with the most devastating being hip fracture …
hallmark of osteoporosis is low trauma fracture, with the most devastating being hip fracture …
Osteoporosis: From osteoscience to neuroscience and beyond
P Kwan - Mechanisms of ageing and development, 2015 - Elsevier
Osteoporosis is well known to be a poly-factorial skeletal disorder characterized by a low
bone mineral density (BMD) at which the risk of developing fracture is remarkably increased …
bone mineral density (BMD) at which the risk of developing fracture is remarkably increased …
Genetic control of bone mass
E Boudin, I Fijalkowski, G Hendrickx… - Molecular and cellular …, 2016 - Elsevier
Bone mineral density (BMD) is a quantitative traits used as a surrogate phenotype for the
diagnosis of osteoporosis, a common metabolic disorder characterized by increased fracture …
diagnosis of osteoporosis, a common metabolic disorder characterized by increased fracture …
Epigenetic pathways regulating bone homeostasis
JB Lian - Bone, 2015 - Elsevier
Epigenetic control of the genome involves a complex series of unique, physiologically
responsive and integrated pathways, each with distinct mechanisms. Insight into epigenetic …
responsive and integrated pathways, each with distinct mechanisms. Insight into epigenetic …
[HTML][HTML] Molecular and cellular mechanisms of osteoporosis
IV Zhivodernikov, TV Kirichenko, YV Markina… - International journal of …, 2023 - mdpi.com
Osteoporosis is a widespread systemic disease characterized by a decrease in bone mass
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …
The molecular genetics of bone formation: implications for therapeutic interventions in bone disorders
PJ Marie - American Journal of Pharmacogenomics, 2001 - Springer
Skeletal biology is a complex process involving the developmental commitment and
differentiation of chondrocytes and osteoblasts which produce and mineralize cartilage and …
differentiation of chondrocytes and osteoblasts which produce and mineralize cartilage and …