[HTML][HTML] Pharmacological and molecular insight on the cardioprotective role of apigenin

SD Thomas, NK Jha, SK Jha, B Sadek, S Ojha - Nutrients, 2023 - mdpi.com
Apigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables.
It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory …

[HTML][HTML] Protective roles of apigenin against cardiometabolic diseases: a systematic review

Y Xu, X Li, H Wang - Frontiers in nutrition, 2022 - frontiersin.org
Apigenin is a flavonoid with antioxidant, anti-inflammatory, and anti-apoptotic activity. In this
study, the potential effects of apigenin on cardiometabolic diseases were investigated in vivo …

[HTML][HTML] Current status and future perspectives on therapeutic potential of apigenin: Focus on metabolic-syndrome-dependent organ dysfunction

W Alam, C Rocca, H Khan, Y Hussain, M Aschner… - Antioxidants, 2021 - mdpi.com
Metabolic syndrome and its associated disorders such as obesity, insulin resistance,
atherosclerosis and type 2 diabetes mellitus are globally prevalent. Different molecules …

Apigenin: A current review on its beneficial biological activities

X Zhou, F Wang, R Zhou, X Song… - Journal of Food …, 2017 - Wiley Online Library
Abstract Apigenin, identified as 4′, 5, 7‐trihydroxyflavone, is a natural flavonoid compound
present in a variety of fruits, vegetables, functional foods, and medicinal plants. Many studies …

Apigenin alleviates STZ-induced diabetic cardiomyopathy

HJ Liu, YL Fan, HH Liao, Y Liu, S Chen, ZG Ma… - Molecular and cellular …, 2017 - Springer
Apigenin is an important component of fruits and vegetables in human daily diets. Several
cellular and animal models have been performed to demonstrate its anti-oxidant and anti …

[HTML][HTML] Apigenin attenuates myocardial ischemia/reperfusion injury via the inactivation of p38 mitogen‑activated protein kinase

X Yang, J Yang, J Hu, X Li… - Molecular Medicine …, 2015 - spandidos-publications.com
Apigenin (Api) is a plant monomer associated with reducing the risk of heart disease.
However, the mechanism of action remains to be fully elucidated. In the present study, it was …

[HTML][HTML] Bio-actives from natural products with potential cardioprotective properties: isolation, identification, and pharmacological actions of apigenin, quercetin, and …

EM Tomou, P Papakyriakopoulou, H Skaltsa… - Molecules, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.
As a result, pharmaceutical and non-pharmaceutical interventions modifying risk factors for …

[HTML][HTML] The therapeutic potential of apigenin

B Salehi, A Venditti, M Sharifi-Rad, D Kręgiel… - International journal of …, 2019 - mdpi.com
Several plant bioactive compounds have exhibited functional activities that suggest they
could play a remarkable role in preventing a wide range of chronic diseases. The largest …

Protective effect of apigenin on ischemia/reperfusion injury of the isolated rat heart

J Hu, Z Li, L Xu, A Sun, X Fu, L Zhang, L Jing… - Cardiovascular …, 2015 - Springer
Apigenin (Api), a mainly bioactive component of Apium graveolens L. var. dulce DC.(a
traditional Chinese medicinal herb), possesses a wide range of biological activities …

Therapeutical properties of apigenin: a review on the experimental evidence and basic mechanisms

Z Mushtaq, NB Sadeer, M Hussain… - … Journal of Food …, 2023 - Taylor & Francis
ABSTRACT Apigenin (4,'5, 7-trihydroxyflavone) is one of the most studied flavonoids with
low toxicity and abundantly present phenolic compound in the plant kingdom. The main …