[HTML][HTML] Single-Cell Transcriptomics of Proliferative Phase Endometrium: Systems Analysis of Cell–Cell Communication Network Using CellChat

Z Fang, Y Tian, C Sui, Y Guo, X Hu, Y Lai… - Frontiers in Cell and …, 2022 - frontiersin.org
The endometrium thickness increases by which endometrial angiogenesis occurs in parallel
with rapid growth of endometrium during the proliferative phase, which is orchestrated by …

Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo–endometrium interplay

M Koel, K Krjutškov, M Saare, K Samuel… - Human …, 2022 - academic.oup.com
STUDY QUESTION Which genes regulate receptivity in the epithelial and stromal cellular
compartments of the human endometrium, and which molecules are interacting in the …

Single cell RNAseq provides a molecular and cellular cartography of changes to the human endometrium through the menstrual cycle

W Wang, F Vilella, I Moreno, W Pan, S Quake… - Fertility and …, 2018 - fertstert.org
Objective Despite its relevance, mechanistic understanding of the human endometrium
remains rudimentary. Here, we characterized the transcriptomic transformation of human …

Bioinformatic analysis reveals the importance of epithelial-mesenchymal transition in the development of endometriosis

M Chen, Y Zhou, H Xu, C Hill, RM Ewing, D He… - Scientific reports, 2020 - nature.com
Background: Endometriosis is a frequently occurring disease in women, which seriously
affects their quality of life. However, its etiology and pathogenesis are still unclear. Methods …

Stromal heterogeneity in the human proliferative endometrium—a single-cell RNA sequencing study

S Queckbörner, C von Grothusen… - Journal of Personalized …, 2021 - mdpi.com
The endometrium undergoes regular regeneration and stromal proliferation as part of the
normal menstrual cycle. To better understand cellular interactions driving the mechanisms in …

Single‐cell sequencing reveals the heterogeneity and intratumoral crosstalk in human endometrial cancer

Z Yu, J Zhang, Q Zhang, S Wei, R Shi, R Zhao… - Cell …, 2022 - Wiley Online Library
Background Endometrial cancer (EC) is one of the most common gynecologic malignancies
with increasing morbidity. Cell–cell and cell‐matrix interactions within the tumour …

Label-free proteomics uncovers energy metabolism and focal adhesion regulations responsive for endometrium receptivity

Q Chen, A Zhang, F Yu, J Gao, Y Liu, C Yu… - Journal of proteome …, 2015 - ACS Publications
The menstrual cycle of the female uterus leads to periodic changes of the endometrium.
These changes are important for developing the endometrial receptivity and for achieving …

Single-cell transcriptomic analysis of endometriosis provides insights into fibroblast fates and immune cell heterogeneity

J Ma, L Zhang, H Zhan, Y Mo, Z Ren, A Shao, J Lin - Cell & Bioscience, 2021 - Springer
Background Endometriosis is an oestrogen-dependent disease with an unclear aetiology
and pathogenesis affecting 6–10% of the global female population, predominantly those of …

Identification and analysis of novel endometriosis biomarkers via integrative bioinformatics

SJ Bae, Y Jo, MK Cho, JS Jin, JY Kim, J Shim… - Frontiers in …, 2022 - frontiersin.org
Endometriosis is a gynecological disease prevalent in women of reproductive age, and it is
characterized by the ectopic presence and growth of the eutopic endometrium. The …

Identification of key genes and pathways in endometriosis by integrated expression profiles analysis

D Cui, Y Liu, J Ma, K Lin, K Xu, J Lin - PeerJ, 2020 - peerj.com
The purpose of this study was to integrate the existing expression profile data on
endometriosis (EM)-related tissues in order to identify the differentially expressed genes. In …