It is now becoming increasingly clear that free radicals contribute to brain damage in several
conditions, such as hyperoxia and trauma. It has been more difficult to prove that free radical …

Although free radicals have been suggested to contribute to ischemic brain damage for
more than 10 years, it is not until quite recently that convincing evidence has been …

This review focuses on the effects that ischemia and hypoxia have on the cerebral cortex
and the cerebellum during different periods of life. The acute interruption or reduction of …

We investigated the pathogenic role of free radical formation in ischemic neuronal death
using radical scavenger, Superoxide dismutase. Cerebral ischemia was produced in the …

Brain reperfusion and/or reoxygenation may be of particular importance in the etiology of
neuronal damage after hypoxicischemic insult in neonates, especially with reference to the …

Although O 2 derived free radical mechanisms have been implicated to cause cerebral
damage associated with ischemia, free radicals have not been measured in this situation. In …

We examined cerebral lipid peroxidation, estimated by a thiobarbituric acid test, in rat brain
regions after 30 minutes of severe forebrain ischemia and at recirculation periods of up to 72 …

Perinatal hypoxia–ischemia (HI) gives rise to inadequate substrate supply to the brain
tissue, resulting in damage to neural cells. Previous studies at different time points of …

The neonatal brain responds differently to hypoxic-ischemic injury and may be more
vulnerable than the mature brain due to a greater susceptibility to oxidative stress. As a …

Free radicals have been suggested to be largely involved in the genesis of ischemic brain
damage, as shown in the protective effects of α-phenyl-N-tert-butyl nitrone (PBN), a spin …