Cardiovascular disease is the leading cause of death, with atherosclerosis the major
underlying cause. While often asymptomatic for decades, atherosclerotic plaque …

BACKGROUND. The identification of patients with high-risk atherosclerotic plaques prior to
the manifestation of clinical events remains challenging. Recent findings question histology …

Cardiovascular disease (CVD) is the most common cause of death in industrialized
countries. One underlying cause is atherosclerosis, which is a systemic disease …

Acute myocardial infarction and stroke are common diseases that cause disability and
mortality, and the underlying mechanism is often the rupture of a vulnerable atherosclerotic …

Atherosclerotic plaque rupture triggers the onset of cardiovascular complications such as
myocardial infarction and stroke, which represent the main cause of death in western …

Purpose To increase the proteome coverage of human atherosclerotic plaques and identify
low‐abundance proteins that may have important functions during the development and …

Atherosclerosis is a chronic inflammatory disease with complex pathobiology and one of the
most common causes of cardiovascular events. The process is characterized by complex …

Biomarkers provide a powerful approach to understanding the spectrum of cardiovascular
diseases. They have application in screening, diagnostic, prognostication, prediction of …

Rationale: Plaque rupture is the proximate cause of most myocardial infarctions and many
strokes. However, the molecular mechanisms that precipitate plaque rupture are unknown …

OBJECTIVES: By using proteomics we isolated and identified proteins that were
expressed/retained in stable and unstable human carotid artery atherosclerotic plaques …