Integrated strategy of LC-MS and network pharmacology for predicting active constituents and pharmacological mechanisms of Ranunculus japonicus Thunb. for …

ZY Wang, FH Chu, NN Gu, Y Wang, D Feng… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Ranunculus japonicus Thunb.(short for R.
japonicus) is a topically applied herb with the activities of removing jaundice, nebula and …

Network Pharmacology-Based Prediction of Active Ingredients and Mechanisms of Lamiophlomis rotata (Benth.) Kudo Against Rheumatoid Arthritis

Y Jiang, M Zhong, F Long, R Yang, Y Zhang… - Frontiers in …, 2019 - frontiersin.org
Background: Lamiophlomis rotata (LR) showed favorable clinical effect and safety on
rheumatoid arthritis (RA), but its active ingredients and mechanisms against RA remain …

Network pharmacology approach to uncover the mechanism governing the effect of radix achyranthis bidentatae on osteoarthritis

L Zhang, X Shi, Z Huang, J Mao, W Mei, L Ding… - … medicine and therapies, 2020 - Springer
Background This study used a network pharmacology approach to elucidate the molecular
mechanism governing the effect of Radix Achyranthis Bidentatae (RAB) on osteoarthritis …

A Systems Biology‐Based Investigation into the Pharmacological Mechanisms of Wu Tou Tang Acting on Rheumatoid Arthritis by Integrating Network Analysis

Y Zhang, D Wang, S Tan, H Xu, C Liu… - Evidence‐Based …, 2013 - Wiley Online Library
Aim. To investigate pharmacological mechanisms of Wu Tou Tang acting on rheumatoid
arthritis (RA) by integrating network analysis at a system level. Methods and Results. Drug …

Virtual Screening Technique Used to Estimate the Mechanism of Adhatoda vasica Nees for the Treatment of Rheumatoid Arthritis Based on Network Pharmacology …

W Wang, Y Zhang, J Luo, R Wang… - Evidence‐Based …, 2020 - Wiley Online Library
Adhatoda vasica Nees (AVN) is commonly used to treat joint diseases such as rheumatoid
arthritis (RA) in ethnic minority areas of China, especially in Tibetan and Dai areas, and its …

A network pharmacology approach to determine the synergetic mechanisms of herb couple for treating rheumatic arthritis

X Xu, J Bi, L Ping, P Li, F Li - Drug Design, Development and …, 2018 - Taylor & Francis
Purpose The purpose of this study was to investigate the therapeutic mechanism (s) of
Clematis chinensis Osbeck/Notopterygium incisum KC Ting ex HT (CN). Methods A network …

Evaluating the therapeutic mechanisms of selected active compounds in Cornus officinalis and Paeonia lactiflora in rheumatoid arthritis via network pharmacology …

Q Li, S Hu, L Huang, J Zhang, G Cao - Frontiers in Pharmacology, 2021 - frontiersin.org
Cornus officinalis Sieb et. Zucc and Paeonia lactiflora Pall. have exhibited favorable
therapeutic effects against rheumatoid arthritis (RA), but the specific mechanisms of their …

Prediction of rhizoma drynariae targets in the treatment of osteoarthritis based on network pharmacology and experimental verification

G Chen, X Liu, J Chen, X Yu, J Luo… - Evidence‐Based …, 2021 - Wiley Online Library
Rhizoma Drynariae has been widely used for the treatment of osteoarthritis (OA), but its
potential targets and molecular mechanisms remain to be further explored. Targets of …

Exploring the pharmacological mechanisms and key active ingredients of total flavonoids from Lamiophlomis rotata (Benth.) Kudo against rheumatoid arthritis based …

H Zhan, R Chen, M Zhong, G Wang, G Jiang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Lamiophlomis rotata (Benth.) Kudo (LR,
Lamiaceae) is a traditional Tibetan medicinal material in China. Tibetan medicine classic …

Lycium ruthenicum Murr. anthocyanins inhibit hyperproliferation of synovial fibroblasts from rheumatoid patients and the mechanism study powered by network …

K Xu, X Qin, Y Zhang, M Yang, H Zheng, Y Li, X Yang… - Phytomedicine, 2023 - Elsevier
Background Rheumatoid arthritis (RA), is a typical autoimmune disease affecting nearly 1%
of the world's population. The dysfunctional hyperproliferation of synovial fibroblast (SF) in …