Background Cancer-induced bone pain (CIBP) is a debilitating chronic pain condition
caused by injury to bone nerve terminals due to primary or metastasized bone tumors. Pain …

Whilst not strictly a neuropathic injury, cancer-induced bone pain (CIBP) is a unique state
with features of neuropathy and inflammation. Recent work has demonstrated that …

Background: Bone cancer pain is currently a major clinical challenge for the management of
cancer patients, and the cellular and molecular mechanisms underlying the spinal …

Cancer-induced bone pain (CIBP) is a type of ongoing or breakthrough pain caused by a
primary bone tumor or bone metastasis. CIBP constitutes a specific pain state with distinct …

Cancer pain is a growing problem, especially with the substantial increase in cancer
survival. Reports indicate that bone metastasis, whose primary symptom is bone pain …

Simple Summary Cancer-induced bone pain severely impairs the quality of life of cancer
patients, many of whom suffer from inadequate pain relief. The development of new …

Cancerous cells can originate in a number of different tissues such as prostate, breast and
lung, but often go undetected and are non-painful. Many types of cancers have a propensity …

Abstract Background Cancer-induced Bone Pain (CIBP) is an important factor affecting their
quality of life of cancer survivors. In addition, current clinical practice and scientific research …

Simple Summary Bone cancer-related chronic pain is mediated by central sensitization
involving neuroinflammation via glial cell activation in the spinal dorsal horn, but not the …

Cancer-induced bone pain (CIBP) is the most common and devastating symptom of bone
metastatic cancer that substantially disrupts patients' quality of life. Currently, there are few …