Neural correlates of risk taking in patients with obsessive-compulsive disorder during risky decision-making

Y Han, F Gao, X Wang, J Xia, H Du, X Liu, S Cai… - Journal of Affective …, 2024 - Elsevier
Background The risk preference during decision-making and the neural substrates involved
in patients with obsessive-compulsive disorder (OCD) remained unclear. The current study …

[HTML][HTML] Doubt in the insula: risk processing in obsessive-compulsive disorder

J Luigjes, M Figee, PN Tobler… - Frontiers in human …, 2016 - frontiersin.org
Extensive cleaning or checking of patients with obsessive-compulsive disorder (OCD) are
often interpreted as strategies to avoid harm and as an expression of the widespread belief …

Altered response to risky decisions and reward in patients with obsessive–compulsive disorder

PS Moreira, J Macoveanu, P Marques, A Coelho… - Journal of Psychiatry and …, 2020 - jpn.ca
Background: Patients with obsessive–compulsive disorder (OCD) employ ritualistic
behaviours to reduce or even neutralize the anxiety provoked by their obsessions. The …

Functional and structural neural indices of risk aversion in obsessive–compulsive disorder (OCD)

R Admon, M Bleich-Cohen, R Weizmant… - Psychiatry Research …, 2012 - Elsevier
Obsessive–compulsive disorder (OCD) patients suffer from risk aversion, which may be
mediated by their exaggerated response to threat and diminished response to reward. In this …

[HTML][HTML] Evidence Accumulation and Neural Correlates of Uncertainty in Obsessive-Compulsive Disorder

YJ Zhao, Y Zhang, Q Wang, L Manssuer, H Cui… - Biological Psychiatry …, 2023 - Elsevier
Background Decision making is frequently associated with risk taking under uncertainty.
Elevated intolerance of uncertainty is suggested to be a critical feature of obsessive …

Further evidence of a dissociation between decision-making under ambiguity and decision-making under risk in obsessive–compulsive disorder

HW Kim, JI Kang, K Namkoong, K Jhung, RY Ha… - Journal of affective …, 2015 - Elsevier
Background Deficits in decision-making have been suggested as a key concept in
understanding the symptoms of obsessive–compulsive disorder (OCD). However, evidence …

Subjective uncertainty and limbic hyperactivation in obsessive‐compulsive disorder

ER Stern, RC Welsh, R Gonzalez… - Human brain …, 2013 - Wiley Online Library
Obsessive‐compulsive disorder (OCD) is often associated with pathological uncertainty
regarding whether an action has been performed correctly or whether a bad outcome will …

A model-based analysis of decision making under risk in obsessive-compulsive and hoarding disorders

GJ Aranovich, DR Cavagnaro, MA Pitt, JI Myung… - Journal of psychiatric …, 2017 - Elsevier
Attitudes towards risk are highly consequential in clinical disorders thought to be prone to
“risky behavior”, such as substance dependence, as well as those commonly associated …

Feeling uncertain despite knowing the risk: Patients with OCD (but not controls) experience known and unknown probabilistic decisions as similarly distressing and …

RJ Jacoby, A Szkutak, J Shin, J Lerner… - Journal of Obsessive …, 2023 - Elsevier
Patients with obsessive compulsive disorder (OCD) present as risk-averse and avoidant of
feared stimuli, yet the literature examining risk aversion in OCD is conflicting. One possible …

Trait-related decision making impairment in obsessive-compulsive disorder: evidence from decision making under ambiguity but not decision making under risk

L Zhang, Y Dong, Y Ji, R Tao, X Chen, J Ye, L Zhang… - Scientific reports, 2015 - nature.com
This study aimed to investigate whether deficits in decision making were potential
endophenotype markers for OCD considering different phases of the disease. Fifty-seven …