Determining protein–protein functional associations by functional rules based on gene ontology and KEGG pathway
Protein–protein interactions (PPIs) describe the direct physical contact of two proteins that
usually results in specific biological functions or regulatory processes. The characterization …
usually results in specific biological functions or regulatory processes. The characterization …
Predicting protein–protein interactions from the molecular to the proteome level
Identification of protein–protein interactions (PPIs) is at the center of molecular biology
considering the unquestionable role of proteins in cells. Combinatorial interactions result in …
considering the unquestionable role of proteins in cells. Combinatorial interactions result in …
Computational methods for predicting protein‐protein interactions using various protein features
Understanding protein‐protein interactions (PPIs) in a cell is essential for learning protein
functions, pathways, and mechanism of diseases. PPIs are also important targets for …
functions, pathways, and mechanism of diseases. PPIs are also important targets for …
Protein-protein interaction (PPI) network: recent advances in drug discovery
A Athanasios, V Charalampos… - Current drug …, 2017 - ingentaconnect.com
Background: The investigation of the cellular components, their interactions and related
functions constitute the major conditions in order to understand the cell as an integrated …
functions constitute the major conditions in order to understand the cell as an integrated …
Evolution of sequence-based bioinformatics tools for protein-protein interaction prediction
Protein-protein interactions (PPIs) are the physical connections between two or more
proteins via electrostatic forces or hydrophobic effects. Identification of the PPIs is pivotal …
proteins via electrostatic forces or hydrophobic effects. Identification of the PPIs is pivotal …
[HTML][HTML] A domain-based approach to predict protein-protein interactions
M Singhal, H Resat - BMC bioinformatics, 2007 - Springer
Background Knowing which proteins exist in a certain organism or cell type and how these
proteins interact with each other are necessary for the understanding of biological processes …
proteins interact with each other are necessary for the understanding of biological processes …
Ensemble learning prediction of protein–protein interactions using proteins functional annotations
Protein–protein interactions are important for the majority of biological processes. A
significant number of computational methods have been developed to predict protein …
significant number of computational methods have been developed to predict protein …
Studying protein–protein interactions: progress, pitfalls and solutions
S Hayes, B Malacrida, M Kiely… - Biochemical Society …, 2016 - portlandpress.com
Signalling proteins are intrinsic to all biological processes and interact with each other in
tightly regulated and orchestrated signalling complexes and pathways. Characterization of …
tightly regulated and orchestrated signalling complexes and pathways. Characterization of …
[HTML][HTML] Benchmark evaluation of protein–protein interaction prediction algorithms
B Dunham, MK Ganapathiraju - Molecules, 2021 - mdpi.com
Protein–protein interactions (PPIs) perform various functions and regulate processes
throughout cells. Knowledge of the full network of PPIs is vital to biomedical research, but …
throughout cells. Knowledge of the full network of PPIs is vital to biomedical research, but …
Discerning molecular interactions: a comprehensive review on biomolecular interaction databases and network analysis tools
Computational analysis of biomolecular interaction networks is now gaining a lot of
importance to understand the functions of novel genes/proteins. Gene interaction (GI) …
importance to understand the functions of novel genes/proteins. Gene interaction (GI) …