Discovery and characterization of long intergenic non-coding RNAs (lincRNA) module biomarkers in prostate cancer: an integrative analysis of RNA-Seq data

W Cui, Y Qian, X Zhou, Y Lin, J Jiang, J Chen, Z Zhao… - BMC genomics, 2015 - Springer
ABSTRACT Background Prostate cancer (PCa) is a leading cause of cancer-related death of
men worldwide. There is an urgent need to develop novel biomarkers for PCa prognosis …

[HTML][HTML] Multi-omics approach for identifying CNV-associated lncRNA signatures with prognostic value in prostate cancer

N Tyagi, S Roy, K Vengadesan, D Gupta - Non-coding RNA Research, 2024 - Elsevier
Background Prostate cancer, the second most prevalent malignancy among men, poses a
significant threat to affected patients' well-being due to its poor prognosis. Novel biomarkers …

Identification of Long Noncoding RNAs That Exert Transcriptional Regulation by Forming RNA–DNA Triplexes in Prostate Cancer

Y Liang, Y Lu, Q Chen, Y Cheng, Y Ma… - International Journal of …, 2023 - mdpi.com
Long noncoding RNAs (lncRNAs) are involved in transcriptional regulation, and their
deregulation is associated with the development of various human cancers, including …

Identification of prognostic biomarkers of prostate cancer with long non-coding RNA-mediated competitive endogenous RNA network

G Ye, L Guo, Y Xing, W Sun… - Experimental and …, 2019 - spandidos-publications.com
Prostate cancer (PCa) is the second most frequently diagnosed male cancer, and no
treatments exist for effective inhibition of metastatic spread of PCa. Long non-coding RNA …

[HTML][HTML] A comprehensive review of the role of long non-coding RNAs in organs with an endocrine function

S Ghafouri-Fard, M Esmaeili, H Shoorei… - Biomedicine & …, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are transcripts with sizes larger than 200 nucleotides and
no/small open reading frame that cannot produce functional proteins. The number of these …

A comparative analysis reveals the dosage sensitivity and regulatory patterns of lncRNA in prostate cancer

Y Liu, R Zhang, N Zhao, Q Zhang, Z Yan… - Molecular …, 2016 - pubs.rsc.org
Although the key roles of long non-coding RNAs (lncRNAs) in multiple diseases are well
documented, the relationship between the lncRNA copy number and expression is …

[HTML][HTML] Long non-coding RNAs: role in testicular cancers

C Bresesti, V Vezzoli, B Cangiano, M Bonomi - Frontiers in Oncology, 2021 - frontiersin.org
In the last few years lncRNAs have gained increasing attention among the scientific
community, thanks to the discovery of their implication in many physio-pathological …

Molecular Mechanisms of Noncoding RNA in the Occurrence of Castration-Resistant Prostate Cancer

Y Lin, H Tan, G Yu, M Zhan, B Xu - International Journal of Molecular …, 2023 - mdpi.com
Although several therapeutic options have been shown to improve survival of most patients
with prostate cancer, progression to castration-refractory state continues to present …

Emerging RNA-Based Therapeutic and Diagnostic Options: Recent Advances and Future Challenges in Genitourinary Cancers

F Tortora, E La Civita, P Trivedi, F Febbraio… - International journal of …, 2023 - mdpi.com
Renal cell carcinoma, bladder cancer, and prostate cancer are the most widespread
genitourinary tumors. Their treatment and diagnosis have significantly evolved over recent …

Long noncoding RNAs: Role and contribution in pancreatic cancer

KT Ramya Devi, D Karthik, TS Mahendran… - …, 2021 - Taylor & Francis
Noncoding RNAs are proclaimed to be expressed in various cancer types and one such
type is found to be pancreatic ductal adenocarcinoma (PDAC). The long noncoding RNAs …