Circulating levels of tissue factor and the risk of thrombosis associated with antiphospholipid syndrome

LQ Tobaldini, FT Arantes, S da Silva Saraiva… - Thrombosis …, 2018 - Elsevier
The mechanisms behind the severe hypercoagulable state in antiphospholipid syndrome
(APS) have not yet been fully elucidated. Knowledge on the etiology of thrombosis in APS is …

Expression of tissue factor mRNA in thrombosis associated with antiphospholipid syndrome

BM Mazetto, M Lazarini, LQ Tobaldini… - Journal of Thrombosis …, 2021 - Springer
Tissue factor (TF) is a procoagulant protein associated with increased risk of thrombotic
events in antiphospholipid syndrome (t-APS). The mechanisms by which TF levels are …

The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome

O Amengual, T Atsumi, MA Khamashta… - Thrombosis and …, 1998 - thieme-connect.com
The antiphospholipid syndrome (APS) is characterised by both arterial and venous
thrombosis, recurrent pregnancy loss and thrombocytopaenia in association with …

Variability of soluble tissue factor in primary antiphospholipid syndrome

MJ Cuadrado, PM Dobado-Berrios… - Thrombosis and …, 1998 - thieme-connect.com
Antiphospholipid syndrome (APS) is a thrombophilic disorder characterized by arterial and
venous thrombosis, thrombocytopenia and recurrent fetal loss associated with the presence …

Up-regulated tissue factor expression in antiphospholipid syndrome

T Atsumi, MA Khamashta, O Amengual… - Thrombosis and …, 1997 - thieme-connect.com
Antiphospholipid syndrome (APS) was described in 1983 as a clinical entity characterized
by arterial and venous thrombosis, thrombocytopenia and recurrent fetal loss associated …

Hypercoagulable state in patients with antiphospholipid syndrome is related to high induced tissue factor expression on monocytes and to low free protein S

JC Reverter, D Tàssies, J Font… - … , and vascular biology, 1996 - Am Heart Assoc
Antiphospholipid antibodies (aPLs) are associated with thrombosis, but the mechanisms of
this thrombotic tendency are unknown. We studied 56 patients (12 with systemic lupus …

Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome

PM Dobado-Berrios, C López-Pedrera… - Thrombosis and …, 1999 - thieme-connect.com
Antiphospholipid antibodies (aPL) may stimulate tissue factor (TF) expression in cultured
endothelial cells and monocytes, but there are discrepancies as to the expression of TF in …

Do antiphospholipid antibodies interfere with tissue factor pathway inhibitor?

EM Jacobsen, PM Sandset, F Wisløff - Thrombosis research, 1999 - Elsevier
This study was conducted to investigate whether antiphospholipid antibodies (APA) can
interfere with the phospholipid-dependent inhibition of coagulation exerted by tissue factor …

Anti-tissue factor pathway inhibitor activity in subjects with antiphospholipid syndrome is associated with increased thrombin generation

M Adams, L Breckler, P Stevens, J Thom… - …, 2004 - haematologica.org
BACKGROUND AND OBJECTIVES: Immunoglobulin G (IgG) fractions from subjects with
antiphospholipid syndrome (aPS) have previously been demonstrated to have inhibitory …

Inflammatory markers in thrombosis associated with primary antiphospholipid syndrome

FT Arantes, BM Mazetto, SS Saraiva… - Journal of Thrombosis …, 2020 - Springer
The role of inflammation in thrombotic complications of primary antiphospholipid syndrome
(PAPS) is controversial. The aim of this study was to evaluate levels of inflammation and …