The use of immune checkpoint inhibitors in oncology and the occurrence of AKI: where do we stand?

R Franzin, GS Netti, F Spadaccino, C Porta… - Frontiers in …, 2020 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are a novel class of immunotherapy drugs that have
improved the treatment of a broad spectrum of cancers as metastatic melanoma, non-small …

Kidney complications of immune checkpoint inhibitors: a review

R Shingarev, IG Glezerman - American Journal of Kidney Diseases, 2019 - Elsevier
Immunologic control of malignancy has long been recognized as an important determinant
of disease progression. Recent advances in immunology have led to the focus on several …

[HTML][HTML] Immune checkpoint inhibitors and immune-related adverse renal events

SM Herrmann, MA Perazella - Kidney international reports, 2020 - Elsevier
Renal toxicities have been increasingly recognized as complications of the immune
checkpoint inhibitors (ICIs). Recent studies have outlined the incidence and potential risk …

Renal adverse effects of immune checkpoints inhibitors in clinical practice: ImmuNoTox study

M Espi, C Teuma, E Novel-Catin, D Maillet… - European Journal of …, 2021 - Elsevier
Abstract Background/objectives Acute Kidney Injury (AKI), induced by Checkpoint Inhibitors
therapies (CPI-induced AKI), is an uncommon but severe Immune-Related Adverse Event …

Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury

B Sprangers, DE Leaf, C Porta, MJ Soler… - Nature Reviews …, 2022 - nature.com
Since their introduction into clinical practice a decade ago, immune checkpoint inhibitors
(ICIs) have had an overwhelming impact on cancer treatment. Use of these agents in …

Renal complications of immune checkpoint blockade

N Murakami, S Motwani, LV Riella - Current problems in cancer, 2017 - Elsevier
Immune checkpoint inhibitors have been approved for a variety of cancer species. Renal
complications in use of these agents are not very common compared with other immune …

Immune checkpoint inhibitor nephrotoxicity: update 2020

S Gupta, FB Cortazar, LV Riella, DE Leaf - Kidney360, 2020 - journals.lww.com
Immune checkpoint inhibitors (ICPIs) have transformed the landscape of oncology, but are
associated with a variety of autoimmune adverse events, including AKI. ICPI-associated AKI …

Cardiorenal complications of immune checkpoint inhibitors

K Sury, MA Perazella, AC Shirali - Nature Reviews Nephrology, 2018 - nature.com
The development of immune checkpoint inhibitors (ICIs) has driven a revolutionary change
in cancer treatment. Although traditional chemotherapeutic agents remain the first-line …

Immune checkpoint inhibitor use in patients with end-stage kidney disease: an analysis of reported cases and literature review

A Kitchlu, KD Jhaveri, B Sprangers… - Clinical Kidney …, 2021 - academic.oup.com
Immune checkpoint inhibitors (ICIs), immunomodulatory antibodies that are used to enhance
the immune system, have substantially improved the prognosis of patients with advanced …

Anti-angiogenic agents in combination with immune checkpoint inhibitors: a promising strategy for cancer treatment

Y Song, Y Fu, Q Xie, B Zhu, J Wang… - Frontiers in …, 2020 - frontiersin.org
Advances in cancer immunity have promoted a major breakthrough in the field of cancer
therapy. This is mainly associated with the successful development of immune checkpoint …