Background: Moderate-severe traumatic brain injury (TBI) is increasingly being understood
as a progressive disorder, with growing evidence of reduced brain volume and white matter …

Traumatic brain injury (TBI) results in neurodegenerative changes that progress for months,
perhaps even years post-injury. However, there is little information on the spatial distribution …

Neuropathological and experimental animal studies indicate that traumatic brain injury (TBI)
results in long-term, neurodegenerative changes. Structural image evaluation using …

BACKGROUND AND PURPOSE: Although mild or moderate traumatic brain injury (TBI) is
known to cause persistent neurologic sequelae, the underlying structural changes remain …

Purpose To investigate longitudinal changes in global and regional brain volume in patients
1 year after mild traumatic brain injury (MTBI) and to correlate such changes with clinical and …

Objectives Characterize the scale and pattern of long-term atrophy in gray matter (GM),
white matter (WM), and cerebrospinal fluid (CSF) in chronic moderate–severe traumatic …

Objective: To assess the relationship between regional brain volume changes and traumatic
brain injury (TBI) severity in patients with and without focal lesions. Methods: Sixty-nine …

Traumatic brain injury leads to significant loss of brain volume, which continues into the
chronic stage. This can be sensitively measured using volumetric analysis of MRI. Here …

Conventional structural imaging is often normal after mild traumatic brain injury (mTBI).
There is a need for structural neuroimaging biomarkers that facilitate detection of milder …

Generalized whole brain volume loss has been well documented in moderate-to-severe
traumatic brain injury (TBI), as has diffuse cerebral atrophy based on magnetic resonance …