pH-responsive dual-loaded nanoplatforms based on polyamidoamine dendrimer with a
hydroxyl-terminated surface (PAMAM–OH), generations 3, 4, and 5 (G3, G4, and G5 …

Polyamidoamine (PAMAM) dendrimers are extensively researched as potential drug
delivery system thanks to their desirable features such as controlled and stable structures …

PAMAM dendrimers are well-known delivery vehicles for various therapeutic agents like
synthetic drugs, natural phytoconstituents, and genetic materials. The tunable …

The objective of this study is to make comprehensive cytotoxicity evaluation and in vitro
characterization of Jeffamine-cored polyamidoamine (PAMAM) dendrimers on L929 cell …

Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …

We present here the development of multifunctional doxorubicin (DOX)-conjugated poly
(amidoamine)(PAMAM) dendrimers as a unique platform for pH-responsive drug release …

HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–
25% of the total cases. It is characterized by aggressive behavior and treatment resistance …

The surface charge of dendrimers is one of the key factors that determine their use in
nanomedicine. Generation 5 poly (amido amine) dendrimers (G5 PAMAM) encapsulating …

Amphiphilic macrocycles, such as p-sulfonatocalix [6] arenes (p-SC6), have demonstrated
great potential in designing synthetic nanovesicles based on self-assembly approaches …

Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …