Binding of hnRNP I–vRNA Regulates Sindbis Virus Structural Protein Expression to Promote Particle Infectivity

CE Westcott, S Qazi, AM Maiocco, S Mukhopadhyay… - Viruses, 2022 - mdpi.com
Alphaviruses cause significant outbreaks of febrile illness and debilitating multi-joint arthritis
for prolonged periods after initial infection. We have previously reported that several host …

Identification and characterization of Sindbis virus RNA-host protein interactions

AT LaPointe, NN Gebhart, ME Meller… - Journal of …, 2018 - Am Soc Microbiol
Arthropod-borne viruses, such as the members of the genus Alphavirus, are a significant
concern to global public health. As obligate intracellular pathogens, RNA viruses must …

hnRNP A1 interacts with the genomic and subgenomic RNA promoters of Sindbis virus and is required for the synthesis of G and SG RNA

H Gui, CW Lu, S Adams, V Stollar, ML Li - Journal of biomedical science, 2010 - Springer
Background Sindbis virus (SV) is the prototype of alphaviruses which are a group of widely
distributed human and animal pathogens. Heterogeneous nuclear ribonucleoprotein …

Increasing the capping efficiency of the Sindbis virus nsP1 protein negatively affects viral infection

AT LaPointe, J Moreno-Contreras, KJ Sokoloski - MBio, 2018 - Am Soc Microbiol
Alphaviruses are arthropod-borne RNA viruses that are capable of causing severe disease
and are a significant burden to public health. Alphaviral replication results in the production …

Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication

IM Cristea, H Rozjabek, KR Molloy, S Karki… - Journal of …, 2010 - Am Soc Microbiol
Sindbis virus (SINV) is the prototype member of the Alphavirus genus, whose members
cause severe human diseases for which there is no specific treatment. To ascertain host …

[HTML][HTML] Heterogeneous nuclear ribonuclear protein K interacts with Sindbis virus nonstructural proteins and viral subgenomic mRNA

AJ Burnham, L Gong, RW Hardy - Virology, 2007 - Elsevier
Alphaviruses are a group of arthropod-borne human and animal pathogens that can cause
epidemics of significant public health and economic consequence. Alphavirus RNA …

Production of noncapped genomic RNAs is critical to Sindbis virus disease and pathogenicity

AT LaPointe, VD Landers, CE Westcott, KJ Sokoloski - MBio, 2020 - Am Soc Microbiol
Alphaviruses are positive-sense RNA viruses that utilize a 5′ cap structure to facilitate
translation of viral proteins and to protect the viral RNA genome. Nonetheless, significant …

Functional analysis of Rift Valley fever virus NSs encoding a partial truncation

JA Head, B Kalveram, T Ikegami - 2012 - journals.plos.org
Rift Valley fever virus (RVFV), belongs to genus Phlebovirus of the family Bunyaviridae,
causes high rates of abortion and fetal malformation in infected ruminants as well as causing …

Tick-borne encephalitis virus nonstructural protein NS5 induces RANTES expression dependent on the RNA-dependent RNA polymerase activity

Z Zheng, J Yang, X Jiang, Y Liu, X Zhang… - The Journal of …, 2018 - journals.aai.org
Tick-borne encephalitis virus (TBEV) is one of the flaviviruses that targets the CNS and
causes encephalitis in humans. The mechanism of TBEV that causes CNS destruction …

Newcastle disease virus V protein targets phosphorylated STAT1 to block IFN-I signaling

X Qiu, Q Fu, C Meng, S Yu, Y Zhan, L Dong, C Song… - PloS one, 2016 - journals.plos.org
Newcastle disease virus (NDV) V protein is considered as an effector for IFN antagonism,
however, the mechanism remains unknown. In this study, the expression of STAT1 and …