Abstract Information available on the risks of neurodevelopmental disorders (NDs)
associated with in utero exposure to valproate (VPA) and to other antiepileptic drugs (AEDs) …

Objectives To assess the association between prenatal exposure to monotherapy with the
antiepileptic drugs (AEDs) most commonly used during pregnancy and the risk of various …

Importance There is concern about neurodevelopmental outcomes associated with prenatal
exposure to valproate and other antiepileptic drugs (AEDs) among children of mothers with …

Purpose Data highlighting valproate as a human teratogen put in context the need to
balance both maternal and fetal needs; maximising maternal health whilst minimising fetal …

Objective Prenatal exposure to the antiseizure medication (ASM) valproate is associated
with an increased risk of congenital malformations, but warnings against the use of valproate …

Beyond its formal indications (epilepsy, bipolar disorder, and migraine), valproate sodium
(VPA) is widely used in a number of other clinical conditions. Recently, however, the US …

Purpose To study patterns of antiepileptic drugs (AED) prescribing, particularly valproate,
during pregnancy over a 10‐year period in the UK, Italy, and France. Methods Data on …

PURPOSE:: To evaluate neurological and cognitive functioning of school-aged (≥ 6 years)
children exposed to valproate monotherapy in utero in a population based, evaluator …

To compare the incidence of foetal malformations (FMs) in pregnant women with epilepsy
treated with different anti-epileptic drugs (AED) and doses, and the influence of seizures …

Importance Valproate is an antiepileptic drug (AED) used in the treatment of epilepsy and
many other neurological and psychiatric disorders. Its use in pregnancy is associated with …