Background Growing evidence has shown that alterations in gut microbiota composition are
associated with multiple autoimmune diseases (ADs). However, it is unclear whether these …

The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

The observational association between gut microbiome and systemic lupus erythematosus
(SLE) has been well documented. However, whether the association is causal remains …

Objective Accumulating evidence from microbial studies have highlighted the modulatory
roles of intestinal microbes in numerous human diseases, however, the shared microbial …

Background Recent studies have shown that the gut microbiota is closely related to the
pathogenesis of Inflammatory Bowel Disease (IBD), but the causal nature is largely …

Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD).
Ulcerative colitis (UC) and Crohn's disease (CD), two subtypes of IBD, are characterized by …

Background The link between the gut microbiota (GM) and Sjögren's Syndrome (SS) is well-
established and apparent. Whether GM is causally associated with SS is uncertain. Methods …

Evidence supports the observational associations of gut microbiota with a variety of
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …

Objective The real causal relationship between human gut microbiota and T1D remains
unclear and difficult to establish. Herein, we adopted a two-sample bidirectional mendelian …

Autoimmune disorders derive from genetic, stochastic, and environmental factors that all
together interact in genetically predisposed individuals. The impact of an imbalanced gut …