Introducing genes into mammalian cells: viral vectors

M Sena-Esteves, G Gao - Cold Spring Harbor Protocols, 2020 - cshprotocols.cshlp.org
Over the years, many different viral vector systems have been developed to take advantage
of the specific biological properties and tropisms of a large number of mammalian viruses …

Versatility of gene therapy vectors through viruses

L Barzon, AL Stefani, M Pacenti… - Expert Opinion on …, 2005 - Taylor & Francis
Several viruses have been engineered for gene therapy applications, and the specific
properties of each viral vector have been exploited to target a variety of inherited and …

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

MA Kay, JC Glorioso, L Naldini - Nature medicine, 2001 - nature.com
Considered by some to be among the simpler forms of life, viruses represent highly evolved
natural vectors for the transfer of foreign genetic information into cells. This attribute has led …

Viral vectors: a look back and ahead on gene transfer technology

L Vannucci, M Lai, F Chiuppesi, L Ceccherini-Nelli… - New …, 2013 - arpi.unipi.it
No matter what their origin, strain and family, viruses have evolved exquisite strategies to
reach and penetrate specific target cells where they hijack the cellular machinery to express …

Vectors for gene expression in mammalian cells

SC Makrides - New comprehensive biochemistry, 2003 - Elsevier
Publisher Summary The achievement of robust and regulated protein production in
mammalian cells is a complex process that requires careful consideration of many factors …

Why do we need new gene therapy viral vectors? Characteristics, limitations and future perspectives of viral vector transduction

R Tomanin, M Scarpa - Current gene therapy, 2004 - ingentaconnect.com
The use of viruses to transduce genes of interest into mammalian cells has been extremely
revolutionary, both in terms of laboratory research and for clinical purposes. This approach …

[图书][B] Viral vectors for gene therapy: methods and protocols

CA Machida - 2008 - books.google.com
Viral Vectors for Gene Therapy: Methods and Protocols consists of 30 ch-ters detailing the
use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex …

Latest development in viral vectors for gene therapy

K Lundstrom - Trends in biotechnology, 2003 - cell.com
Gene therapy includes the application of various viral vectors, which represent most types
and families of viruses, suitable for infection of mammalian host cells. Both hereditary …

Using viral vectors as gene transfer tools (Cell Biology and Toxicology Special Issue: ETCS-UK 1 day meeting on genetic manipulation of cells)

JL Howarth, YB Lee, JB Uney - Cell biology and toxicology, 2010 - Springer
In recent years, the development of powerful viral gene transfer techniques has greatly
facilitated the study of gene function. This review summarises some of the viral delivery …

Advances in the development of non-human viral DNA-vectors for gene delivery

P Loser, A Huser, M Hillgenberg, D Kumin… - Current gene …, 2002 - ingentaconnect.com
Within the last two decades, various vectors based on human viruses have been developed
as gene transfer vehicles for gene therapy applications and vaccination. However, one yet …