Disseminated intravascular coagulation: new identity as endotheliopathy-associated vascular microthrombotic disease based on in vivo hemostasis and endothelial …

JC Chang - Thrombosis Journal, 2020 - Springer
Disseminated intravascular coagulation (DIC) can be correctly redefined as disseminated
intravascular microthrombosis based on “two-path unifying theory” of in vivo …

Disseminated intravascular coagulation: is it fact or fancy?

JC Chang - Blood Coagulation & Fibrinolysis, 2018 - journals.lww.com
Abstract 'Disseminated intravascular coagulation (DIC)'occurs commonly in critical illnesses
such as sepsis, trauma, cancer, and complications of surgery and pregnancy. Mortality is …

TTP-like syndrome: novel concept and molecular pathogenesis of endotheliopathy-associated vascular microthrombotic disease

JC Chang - Thrombosis journal, 2018 - Springer
TTP is characterized by microangiopathic hemolytic anemia and thrombocytopenia
associated with brain and kidney dysfunction. It occurs due to ADAMTS13 deficiency. TTP …

Differences and similarities between disseminated intravascular coagulation and thrombotic microangiopathy

H Wada, T Matsumoto, K Suzuki, H Imai, N Katayama… - Thrombosis journal, 2018 - Springer
Introduction Both disseminated intravascular coagulation (DIC) and thrombotic
microangiopathy (TMA) cause microvascular thrombosis associated with thrombocytopenia …

[PDF][PDF] Thrombocytopenia in critically ill patients due to vascular microthrombotic disease: pathogenesis based on “two activation theory of the endothelium”

JC Chang - Vascul Dis Ther, 2017 - academia.edu
The pathogenesis of thrombocytopenia in critically ill patients (TCIP) has not been
established yet. Based on “two-activation theory of the endothelium”, TCIP is a manifestation …

[HTML][HTML] Communication from the Scientific Standardization Committees of the International Society on Thrombosis and Haemostasis on vascular endothelium-related …

T Iba, JH Levy, J Thachil, S Susen, M Levi… - Journal of Thrombosis …, 2023 - Elsevier
Disseminated intravascular coagulation (DIC) is not a disease criterion but a
pathomechanistic process that accompanies various underlying diseases. According to the …

Thrombogenesis and thrombotic disorders based on 'two-path unifying theory of hemostasis': philosophical, physiological, and phenotypical interpretation

JC Chang - Blood Coagulation & Fibrinolysis, 2018 - journals.lww.com
Hemostasis, endowed to human to protect lives, is a process of logical blood clotting system
to prevent blood loss in vascular injury. However, the notion that deadly thrombosis occurs …

Hemostasis based on a novel 'two-path unifying theory'and classification of hemostatic disorders

JC Chang - Blood Coagulation & Fibrinolysis, 2018 - journals.lww.com
Hemostasis is the most important protective mechanism for human survival following harmful
vascular damage caused by internal disease or external injury. Physiological mechanism of …

Disseminated intravascular coagulation and its immune mechanisms

NI Popescu, C Lupu, F Lupu - Blood, The Journal of the …, 2022 - ashpublications.org
Disseminated intravascular coagulation (DIC) is a syndrome triggered by infectious and
noninfectious pathologies characterized by excessive generation of thrombin within the …

A short contemporary history of disseminated intravascular coagulation

M Levi, T van der Poll - Seminars in thrombosis and …, 2014 - thieme-connect.com
Disseminated intravascular coagulation (DIC) is a syndrome characterized by systemic
intravascular activation of coagulation, leading to a widespread deposition of fibrin in the …