Quercetin inhibits TNF-α induced HUVECs apoptosis and inflammation via downregulating NF-kB and AP-1 signaling pathway in vitro

T Chen, X Zhang, G Zhu, H Liu, J Chen, Y Wang, X He - Medicine, 2020 - journals.lww.com
Background: Quercetin, a major flavonol, wildly exists in plantage, which has been reported
to have an anti-apoptosis and anti-inflammation effects on vascular endothelial cells, but its …

Quercetin attenuates high fructose feeding-induced atherosclerosis by suppressing inflammation and apoptosis via ROS-regulated PI3K/AKT signaling pathway

XL Lu, CH Zhao, XL Yao, H Zhang - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Quercetin is a dietary flavonoid compound extracted from various plants, such as apple and
onions. Previous studies have revealed its anti-inflammatory, anti-cancer, antioxidant and …

Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells

SC Cheng, YH Wu, WC Huang, JHS Pang, TH Huang… - Cytokine, 2019 - Elsevier
Quercetin is a flavonoid polyphenolic compound present in fruits and vegetables that has
proven anti-inflammatory activity. The goal of the present investigation was to investigate the …

Quercetin inhibits the production of IL-1β-induced inflammatory cytokines and chemokines in ARPE-19 cells via the MAPK and NF-κB signaling pathways

SC Cheng, WC Huang, JH S. Pang, YH Wu… - International journal of …, 2019 - mdpi.com
Quercetin, a bioflavonoid derived from vegetables and fruits, exerts anti-inflammatory effects
in various diseases. Our previous study revealed that quercetin could suppress the …

Quercetin attenuates cardiomyocyte apoptosis via inhibition of JNK and p38 mitogen-activated protein kinase signaling pathways

C Li, T Wang, C Zhang, J Xuan, C Su, Y Wang - Gene, 2016 - Elsevier
Abstract Quercetin (Que), a plant-derived flavonoid, possesses various biological functions.
Moreover, Que exerts multiple beneficial actions in treatment of cardiovascular diseases and …

Quercetin potentiates apoptosis by inhibiting nuclear factor-kappaB signaling in H460 lung cancer cells

HS Youn, JC Jeong, YS Jeong, EJ Kim… - Biological and …, 2013 - jstage.jst.go.jp
The herbal flavonoid quercetin inhibits the growth of various cancer cells, but how it affects
human cancer cells, particularly lung cancer cells, is unclear. We investigated the anticancer …

RETRACTED: Quercetin improve ischemia/reperfusion‐induced cardiomyocyte apoptosis in vitro and in vivo study via SIRT1/PGC‐1α signaling

J Tang, L Lu, Y Liu, J Ma, L Yang, L Li… - Journal of Cellular …, 2019 - Wiley Online Library
Aim To evaluate the effects of quercetin to improve ischemia/reperfusion‐induced
cardiomyocyte apoptosis in vitro and in vivo study. Methods The cells were divided into five …

Quercetin induces apoptosis by activating caspase-3 and regulating Bcl-2 and cyclooxygenase-2 pathways in human HL-60 cells

G Niu, S Yin, S Xie, Y Li, D Nie, L Ma… - … Biochim Biophys Sin, 2011 - academic.oup.com
Quercetin is one of the naturally occurring dietary flavonol compounds. It is present
abundantly in plants and has chemopreventive and anticancer effects. To investigate its …

The protective effect of quercetin on endothelial cells injured by hypoxia and reoxygenation

MT Li, J Ke, SF Guo, Y Wu, YF Bian, LL Shan… - Frontiers in …, 2021 - frontiersin.org
Background: Cerebral small vessel disease (CSVD) is a group of clinical syndromes
covering all pathological processes of small vessels in the brain, which can cause stroke …

[HTML][HTML] Quercetin inhibits the proliferation and metastasis of human non-small cell lung cancer cell line: the key role of Src-mediated fibroblast growth factor-inducible …

Y Dong, J Yang, L Yang, P Li - Medical science monitor …, 2020 - ncbi.nlm.nih.gov
Background Quercetin (Que) is reported to induce apoptosis of lung cancer cells. Src is
closely related to the progression of non-small cell lung cancer (NSCLC) and can be …