Adolescence is a critical period of development with robust behavioral, morphological,
hormonal, and neurochemical changes including changes in brain regions implicated in the …

In recent years, more than half of all drug overdose deaths in United States involved an
opioid. To address this epidemic, antecedents to opioid misuse must be identified and …

Although prior research has provided data on nonmedical use of opioids in adolescents,
studies examining the heterogeneity of risk are limited. The present study extends prior …

Objective To examine whether young adult opioid misuse reflects a general tendency
toward substance use and is influenced by general substance use risk or whether it is a …

Background. Prescription opioids are the most frequently misused class of prescription drug
among young adults aged 18–25, yet trajectories of opioid misuse and escalation are …

Background Studies have shown the frequency of drug misuse is important in the
development of a substance use disorder, but little is known about this relationship in the …

Abstract Background and Aims Some adolescents and young adults (termed “youth”)
prescribed an opioid will develop opioid use disorder or experience overdose. This study …

Background: Examining opioid use profiles over time and related factors among young
adults is crucial to informing prevention efforts. Objectives: This study analyzed baseline …

Over the past decade, opioid abuse/misuse has grown from a local problem into a national
crisis, causing the US Health and Human Services (HSS) to declare a public health …

BACKGROUND AND OBJECTIVE: Legitimate opioid use is associated with an increased
risk of long-term opioid use and possibly misuse in adults. The objective of this study was to …