Selenium and inflammation: underlying anti-inflammatory mechanisms

LH Duntas - Hormone and metabolic research, 2009 - thieme-connect.com
The essential trace element selenium (Se), in the form of selenoproteins, plays a pivotal role
in the antioxidant defense system of the cell. There is evidence that Se may confer benefits …

The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities

Z Huang, AH Rose, PR Hoffmann - Antioxidants & redox signaling, 2012 - liebertpub.com
Abstract Dietary selenium (] Se), mainly through its incorporation into selenoproteins, plays
an important role in inflammation and immunity. Adequate levels of Se are important for …

[HTML][HTML] Selenium and selenoproteins: It's role in regulation of inflammation

S Hariharan, S Dharmaraj - Inflammopharmacology, 2020 - Springer
Selenium is an essential immunonutrient which holds the human's metabolic activity with its
chemical bonds. The organic forms of selenium naturally present in human body are …

[HTML][HTML] The role of selenium in pathologies: An updated review

G Barchielli, A Capperucci, D Tanini - Antioxidants, 2022 - mdpi.com
Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

Toward improved human health: Efficacy of dietary selenium on immunity at the cellular level

X Xia, X Zhang, M Liu, M Duan, S Zhang, X Wei… - Food & function, 2021 - pubs.rsc.org
Selenium, an essential trace element in the body, participates in various biological
processes in the form of selenoproteins. In humans, a suitable concentration of selenium is …

Selenium attenuates lipopolysaccharide-induced oxidative stress responses through modulation of p38 MAPK and NF-κB signaling pathways

SH Kim, VJ Johnson, TY Shin… - … Biology and Medicine, 2004 - journals.sagepub.com
Lipopolysaccharide (LPS) produces reactive oxygen species (ROS) and nitric oxide (NO) in
macrophages. These molecules are involved in inflammation associated with endotoxic …

Biological activity of selenium: Revisited

JK Wrobel, R Power, M Toborek - IUBMB life, 2016 - Wiley Online Library
Selenium (Se) is an essential micronutrient that exerts multiple and complex effects on
human health. Se is essential for human well‐being largely due to its potent antioxidant, anti …

[HTML][HTML] Selenium and selenoproteins in health

F Zhang, X Li, Y Wei - Biomolecules, 2023 - mdpi.com
Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …

High-dose selenium substitution in sepsis: a prospective randomized clinical trial

J Valenta, H Brodska, T Drabek, J Hendl… - Intensive care medicine, 2011 - Springer
Objective Systemic inflammatory response syndrome (SIRS) and sepsis remain the leading
cause of death in the critically ill. A reduction in the antioxidant capacity, including …

Relationship between selenium status, selenoproteins and COVID-19 and other inflammatory diseases: A critical review

A Golin, AA Tinkov, M Aschner, M Farina… - Journal of Trace …, 2023 - Elsevier
The antioxidant effects of selenium as a component of selenoproteins has been thought to
modulate host immunity and viral pathogenesis. Accordingly, the association of low dietary …