Pre-eclampsia and eclampsia pathogenesis utilizes iron released by a hemolytic protozoan parasite

K Roe - Medical Hypotheses, 2023 - Elsevier
Pre-eclampsia and eclampsia cause unfortunate pregnancies, and currently affect 8% to
10% of pregnancies world-wide, causing∼ 16% of maternal mortalities. The causations of …

[HTML][HTML] A dormant microbial component in the development of preeclampsia

DB Kell, LC Kenny - Frontiers in medicine, 2016 - frontiersin.org
Preeclampsia (PE) is a complex, multisystem disorder that remains a leading cause of
morbidity and mortality in pregnancy. Four main classes of dysregulation accompany PE …

Estrogen-dependent changes in serum iron levels as a translator of the adverse effects of estrogen during infection: a conceptual framework

M Hamad, S Awadallah - Medical Hypotheses, 2013 - Elsevier
Elevated levels of estrogen often associate with increased susceptibility to infection. This
has been attributed to the ability of estrogen to concomitantly enhance the growth and …

[HTML][HTML] Iron metabolism and ferroptosis: A pathway for understanding preeclampsia

KE Gumilar, B Priangga, CH Lu, EG Dachlan… - Biomedicine & …, 2023 - Elsevier
Preeclampsia (PE) is a serious medical condition that poses a significant health risk to
women and children worldwide, particularly in the middle-and low-income countries. It is a …

[HTML][HTML] Iron and parasites

R Arroyo, T Ochoa, JH Tai… - BioMed Research …, 2015 - ncbi.nlm.nih.gov
In this special issue, we analyze the importance of iron in the host-parasite interplay. Iron is
a transition element and the fourth most abundant element in the Earth's crust. Iron is vital for …

The impact of iron overload and ferroptosis on reproductive disorders in humans: implications for preeclampsia

SW Ng, SG Norwitz, ER Norwitz - International journal of molecular …, 2019 - mdpi.com
Iron is an essential element for the survival of most organisms, including humans. Demand
for iron increases significantly during pregnancy to support growth and development of the …

Iron, infections, and anemia of inflammation

RL Jurado - Clinical infectious diseases, 1997 - academic.oup.com
Iron is essential to all microorganisms. To obtain iron from the very low concentrations
present in their environment, microorganisms have developed sophisticated mechanisms …

Role of iron in the pathogenesis of endometriosis

S Gupta, A Harlev, A Agarwal, S Gupta… - Endometriosis: A …, 2015 - Springer
Iron can accumulate in the peritoneal fluid, macrophages, and endometrial lesions in
women with endometriosis. The process begins as erythrocytes are phagocytized by …

Infections associated with iron administration

M Nairz, G Weiss - Met Ions Life Sci, 2019 - degruyter.com
A dynamic interplay between the host and pathogen determines the course and outcome of
infections. A central venue of this interplay is the struggle for iron, a micronutrient essential to …

Human infectious diseases and risk of preeclampsia: an updated review of the literature

M Nourollahpour Shiadeh, Z Behboodi Moghadam… - Infection, 2017 - Springer
Background Preeclampsia (PE) is one of the major causes of maternal and perinatal
morbidity and mortality, especially in low-and middle-income countries. In recent years, a …