Non-coding RNAs in cancer diagnosis and therapy: focus on lung cancer

P Le, G Romano, P Nana-Sinkam, M Acunzo - Cancers, 2021 - mdpi.com
Simple Summary Researchers have spent nearly two decades unraveling the roles of non-
coding RNAs in cancer biology. In recent years, deep transcriptomic profiling of tissue and …

The emerging roles of long noncoding RNAs as hallmarks of lung cancer

J Jiang, Y Lu, F Zhang, J Huang, X Ren… - Frontiers in oncology, 2021 - frontiersin.org
Noncoding ribonucleic acids (ncRNAs) are closely associated with tumor initiation, growth,
and progress in lung cancer. Long ncRNAs (lncRNAs), as one of the three subclasses of …

Long non‐coding RNAs in non‐small cell lung cancer as biomarkers and therapeutic targets

J Chen, R Wang, K Zhang… - Journal of cellular and …, 2014 - Wiley Online Library
Lung cancer‐associated mortality is the most common cause of cancer death worldwide.
Non‐coding RNA s (nc RNA s), with no protein‐coding ability, have multiple biological roles …

[HTML][HTML] Non-coding RNAs in lung cancer

B Ricciuti, C Mecca, L Crinò, S Baglivo, M Cenci… - …, 2014 - ncbi.nlm.nih.gov
The discovery that protein-coding genes represent less than 2% of all human genome, and
the evidence that more than 90% of it is actively transcribed, changed the classical point of …

Long noncoding RNAs: new insights into non-small cell lung cancer biology, diagnosis and therapy

B Ricciuti, C Mencaroni, L Paglialunga, F Paciullo… - Medical oncology, 2016 - Springer
Recent advances in tiling array and high throughput analyses revealed that at least 87.3% of
the human genome is actively transcribed, though< 3% of the human genome encodes …

Long non-coding RNAs as emerging targets in lung cancer

J Gencel-Augusto, W Wu, TG Bivona - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (LncRNAs) are non-protein coding molecules
longer than 200 nucleotides. They play essential roles in normal cell function and …

[HTML][HTML] Non-coding RNA: a new tool for the diagnosis, prognosis, and therapy of small cell lung cancer

J Huang, J Peng, L Guo - Journal of Thoracic Oncology, 2015 - Elsevier
In recent years, novel classes of noncoding RNAs (ncRNAs) have been discovered, which
are implicated in diverse functional and regulatory activities. Growing evidence indicates …

The emerging role and promise of long noncoding RNAs in lung cancer treatment

Y Chen, C Li, Y Pan, S Han, B Feng, Y Gao… - Cellular Physiology and …, 2016 - karger.com
Lung cancer is the leading cause of cancer death around the world. The advanced
discovery of numerous long noncoding RNAs (lncRNAs) has dramatically changed the …

Long noncoding RNAs in lung cancer

A Roth, S Diederichs - Long Non-coding RNAs in Human Disease, 2015 - Springer
Despite great progress in research and treatment options, lung cancer remains the leading
cause of cancer-related deaths worldwide. Oncogenic driver mutations in protein-encoding …

Non-coding RNAs, epigenetics, and cancer: tying it all together

HJ Ferreira, M Esteller - Cancer and Metastasis Reviews, 2018 - Springer
While only a small part of the human genome encodes for proteins, biological functions for
the so-called junk genome are increasingly being recognized through high-throughput …