Several rare genetic variations of human XDH have been shown to alter xanthine
oxidoreductase (XOR) activity leading to impaired purine catabolism. However, XOR is a …

The authors regret an error in transcription for figure creation resulted in an incorrect
representation of the data for Fig. 6E. The correct panel image is shown below. All data and …

Xanthine oxidoreductase (XOR) is an enzyme that catalyzes the two-step reaction from
hypoxanthine to xanthine and from xanthine to uric acid in purine metabolism. XOR …

Reactive oxygen species are generated by various biological systems, including NADPH
oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute …

Reactive oxygen species are generated by various systems, including NADPH oxidases,
xanthine oxidoreductase (XOR) and mitochondrial respiratory enzymes, and contribute to …

Human xanthine oxidoreductase (XOR) is a multiple-level regulated enzyme, resulting from
a complicated evolutionary process that assigned it many physiological roles. The main …

Xanthine oxidoreductase (XOR) catalyzes the conversion of hypoxanthine to xanthine and
xanthine to uric acid with concomitant reduction of either NAD+ or O2. The enzyme is a …

Uric acid is the end product of purine catabolism in humans and is capable of acting as both
an antioxidant scavenging reactive oxygen species and conditionally a pro‐oxidant …

Objective Xanthine oxidase (XO) catalyzes the oxidation of endogenous and exogenous
purines and pyrimidines. In this study, we speculated that individual variations in XO activity …

Classical xanthinuria is a rare inherited metabolic disorder caused by either isolated
xanthine dehydrogenase (XDH) deficiency (type I) or combined XDH and aldehyde oxidase …