Innate immunity is the frontline of defense against infections and tissue damage. It is a fast
and semi-specific response involving a myriad of processes essential for protecting the …

Innate immunity is one of the most ancient and conserved aspect of the immune system. It is
responsible for an anti-infective response and has been intrinsically linked to the generation …

Fighting external pathogens requires an ever-changing immune system that relies on tight
regulation of gene expression. Transcriptional control is the first step to build efficient …

RNA acts as an immunostimulatory molecule in the innate immune system to activate
nucleic acid sensors. It functions as an intermediate, conveying genetic information to …

Innate immune response is triggered by pathogen components, like lipopolysaccharides
(LPS) of gram-negative bacteria. LPS initiates Toll-like receptor 4 (TLR4) signaling, which …

Much has been learned about the molecular and cellular components critical for the control
of immune responses and tolerance. It remains a challenge, however, to control the immune …

Post‐transcriptional mechanisms that modulate global and/or transcript‐specific m RNA
stability and translation contribute to the rapid and flexible control of gene expression in …

Pathogen sensing via pattern recognition receptors triggers massive reprogramming of
macrophage gene expression. While the signaling cascades and transcription factors that …

Immune response plays a fundamental role in protecting the organism from infections;
however, dysregulation often occurs and can be detrimental for the organism, leading to a …

RNA-binding proteins (RBPs) are essential for the development and function of the immune
system. They interact dynamically with RNA to control its biogenesis and turnover by …