Recent achievements of bioluminescence imaging based on firefly luciferin-luciferase system

S Li, Z Ruan, H Zhang, H Xu - European Journal of Medicinal Chemistry, 2021 - Elsevier
Bioluminescence imaging (BLI) is a newly developed noninvasive visual approach which
facilitates the understanding of a plethora of biological processes in vitro and in vivo due to …

[HTML][HTML] How to select firefly luciferin analogues for in vivo imaging

R Saito-Moriya, J Nakayama, G Kamiya… - International Journal of …, 2021 - mdpi.com
Bioluminescence reactions are widely applied in optical in vivo imaging in the life science
and medical fields. Such reactions produce light upon the oxidation of a luciferin (substrate) …

Beyond luciferase-luciferin system: Modification, improved imaging and biomedical application

Y Jiang, X Shi, C Tang, F Wang - Coordination Chemistry Reviews, 2023 - Elsevier
The bioluminescence signal generated by the luciferase-luciferin interaction, exploited for
real-time and continuous monitoring of numerous biochemical processes in living cells and …

Cage the firefly luciferin!–a strategy for developing bioluminescent probes

J Li, L Chen, L Du, M Li - Chemical Society Reviews, 2013 - pubs.rsc.org
Bioluminescent imaging (BLI) has been widely applicable in the imaging of process
envisioned in life sciences. As the most conventional technique for BLI, the firefly luciferin …

Recent Applications and Future Perspectives of Chemiluminescent and Bioluminescent Imaging Technologies

IM Mostafa, A Abdussalam, YT Zholudov… - … & Biomedical Imaging, 2023 - ACS Publications
Imaging technologies based on chemiluminescence (CL) and bioluminescence (BL) have
seen a tremendous growth in the past decade due to their extensive contributions to …

[HTML][HTML] Chemiluminescence and bioluminescence imaging for biosensing and therapy: in vitro and in vivo perspectives

Y Yan, P Shi, W Song, S Bi - Theranostics, 2019 - ncbi.nlm.nih.gov
Chemiluminescence (CL) and bioluminescence (BL) imaging technologies, which require
no external light source so as to avoid the photobleaching, background interference and …

Constructing firefly luciferin bioluminescence probes for in vivo imaging

X Yang, X Qin, H Ji, L Du, M Li - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Bioluminescence imaging (BLI) is a widely applied visual approach for real-time detecting
many physiological and pathological processes in a variety of biological systems. Based on …

[HTML][HTML] Evaluating brightness and spectral properties of click beetle and firefly luciferases using luciferin analogues: identification of preferred pairings of luciferase …

G Zambito, N Gaspar, Y Ridwan, MP Hall, C Shi… - Molecular Imaging and …, 2020 - Springer
Purpose Currently, a variety of red and green beetle luciferase variants are available for
bioluminescence imaging (BLI). In addition, new luciferin analogues providing longer …

[HTML][HTML] Emerging tools for bioluminescence imaging

G Zambito, C Chawda, L Mezzanotte - Current Opinion in Chemical Biology, 2021 - Elsevier
Bioluminescence (BL) relies on the enzymatic reaction between luciferase, a substrate
conventionally named luciferin, and various cofactors. BL imaging has become a widely …

Luciferin derivatives for enhanced in vitro and in vivo bioluminescence assays

R Shinde, J Perkins, CH Contag - Biochemistry, 2006 - ACS Publications
In vivo bioluminescence imaging has become a cornerstone technology for preclinical
molecular imaging. This imaging method is based on light-emitting enzymes, luciferases …