To date, numerous genes have been identified to encode helicases, which are enzymes that
unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes to regulate DNA replication …

Recent progress in pharmaceutical sciences has made it possible for us to live longer and
longer. For example, antibiotics and vaccines have been developed that were successfully …

DNA helicases have emerged as a prominent class of nucleic acid-metabolizing enzymes
that play important roles in genome maintenance and cellular homeostasis. DNA helicases …

Helicases are enzymes that unwind DNA-DNA and RNA-DNA duplexes play important roles
in many DNA metabolic activities like replication, transcription, recombination and repair …

DNA helicases are molecular motors that catalyse the unwinding of energetically unstable
structures into single strands and have therefore an essential role in nearly all metabolism …

ABSTRACT DNA helicases are required for virtually every aspect of DNA metabolism,
including replication, repair, recombination and transcription. A comprehensive description …

DNA helicases are a highly conserved group of enzymes that unwind DNA. They function in
all processes in which access to single-stranded DNA is required, including DNA replication …

DNA helicases, known for their fundamentally important roles in genomic stability, are high
profile players in cancer. Not only are there monogenic helicase disorders with a strong …

DNA helicases use the energy of ATP hydrolysis to disrupt DNA base pairing and displace
proteins from DNA in order to facilitate replication, recombination, transcription, and repair …

Double-stranded DNA and RNA, and DNA/RNA hybrids form naturally in cells between two
nucleic acid strands containing complementary sequences. However, these double …