[PDF][PDF] Transcription regulatory systems of the human helicases
F Uchiumi - Advances in Medicine and Biology, 2020 - researchgate.net
To date, numerous genes have been identified to encode helicases, which are enzymes that
unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes to regulate DNA replication …
unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes to regulate DNA replication …
Helicases and human diseases
F Uchiumi, M Seki, Y Furuichi - Frontiers in genetics, 2015 - frontiersin.org
Recent progress in pharmaceutical sciences has made it possible for us to live longer and
longer. For example, antibiotics and vaccines have been developed that were successfully …
longer. For example, antibiotics and vaccines have been developed that were successfully …
DNA Helicases: Mechanisms, Biological Pathways, and Disease Relevance
RM Brosh Jr - Genes, 2021 - mdpi.com
DNA helicases have emerged as a prominent class of nucleic acid-metabolizing enzymes
that play important roles in genome maintenance and cellular homeostasis. DNA helicases …
that play important roles in genome maintenance and cellular homeostasis. DNA helicases …
Helicase domain containing proteins in human disorders
AS Balajee, C ApRhys - Current Genomics, 2001 - ingentaconnect.com
Helicases are enzymes that unwind DNA-DNA and RNA-DNA duplexes play important roles
in many DNA metabolic activities like replication, transcription, recombination and repair …
in many DNA metabolic activities like replication, transcription, recombination and repair …
DNA helicases and human diseases
M Uhring, A Poterszman - Medecine Sciences: M/S, 2006 - europepmc.org
DNA helicases are molecular motors that catalyse the unwinding of energetically unstable
structures into single strands and have therefore an essential role in nearly all metabolism …
structures into single strands and have therefore an essential role in nearly all metabolism …
DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases
SG Mackintosh, KD Raney - Nucleic acids research, 2006 - academic.oup.com
ABSTRACT DNA helicases are required for virtually every aspect of DNA metabolism,
including replication, repair, recombination and transcription. A comprehensive description …
including replication, repair, recombination and transcription. A comprehensive description …
DNA helicases, genomic instability, and human genetic disease
AJ Van Brabant, R Stan, NA Ellis - Annual review of genomics …, 2000 - annualreviews.org
DNA helicases are a highly conserved group of enzymes that unwind DNA. They function in
all processes in which access to single-stranded DNA is required, including DNA replication …
all processes in which access to single-stranded DNA is required, including DNA replication …
DNA helicases and their roles in cancer
DNA helicases, known for their fundamentally important roles in genomic stability, are high
profile players in cancer. Not only are there monogenic helicase disorders with a strong …
profile players in cancer. Not only are there monogenic helicase disorders with a strong …
Human RECQ helicases: roles in cancer, aging, and inherited disease
JM Sidorova, RJ Monnat Jr - Advances in Genomics and Genetics, 2014 - Taylor & Francis
DNA helicases use the energy of ATP hydrolysis to disrupt DNA base pairing and displace
proteins from DNA in order to facilitate replication, recombination, transcription, and repair …
proteins from DNA in order to facilitate replication, recombination, transcription, and repair …
Helicase Dysfunctions in Human Diseases
Double-stranded DNA and RNA, and DNA/RNA hybrids form naturally in cells between two
nucleic acid strands containing complementary sequences. However, these double …
nucleic acid strands containing complementary sequences. However, these double …